Results 151 to 160 of about 1,521,587 (360)

Selected Literature on Conflict Prevention, Crime Prevention, Terrorism Prevention and Violence Prevention

open access: yesPerspectives on Terrorism, 2011
Monographs, Edited Volumes, Non-conventional Literature and Prime Articles published since 2001, selected by Eric Price (Professional Information Specialist)
Eric Price
doaj  

Formal Verification of Air Traffic Conflict Prevention Bands Algorithms [PDF]

open access: yes
In air traffic management, a pairwise conflict is a predicted loss of separation between two aircraft, referred to as the ownship and the intruder. A conflict prevention bands system computes ranges of maneuvers for the ownship that characterize regions ...
Dowek, Gilles   +2 more
core   +1 more source

The EU’s Nobel Prize means that it must do even more to overcome its current crises, and increase its role as a force for peace and prosperity [PDF]

open access: yes, 2012
This morning the Nobel Prize Committee announced that they had awarded its annual peace prize to the European Union in recognition for its efforts in promoting peace and reconciliation in Europe over the past 60 years. Maurice Fraser argues that it would
Fraser, Maurice
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Crisis Prevention: Tackling Horizontal Inequalities [PDF]

open access: yes
Civil wars not only cause huge amounts of human distress, but are also a major cause of low-incomes. Hence their prevention should be a central aspect of poverty reduction strategies.
Frances Stewart
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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