Results 101 to 110 of about 669,495 (266)
Interpretation as conflict resolution Interpretation as conflict resolution
Interpreting words, sentences and discourse is a process of resolving conflicts between the requirements of various general constraints on the correspondence between form and meaning and the interaction between lexicon and context. In this paper the fruitfulness of taking an optimality-theoretic approach to semantic conflict resolution by ...
Henriëtte de Swart, Joost Zwarts
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The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
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Transactional sexual relationships (TSRs) take varied forms, with research emphasizing TSRs’ inherent risks, primarily to women. In South Africa, Blessed relationships have emerged as a prominent type of TSR.
Gavin George +2 more
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
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Intimate partner violence (IPV) remains a significant global health and human rights problem affecting one in three women globally and in Colombia. While IPV and feminicide are preventable, little research has documented public health-justice programs ...
Courtenay Sprague +4 more
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Parent–adolescent conflict is normative, and whether and how conflicts are resolved tend to be more important for adolescent adjustment than the actual occurrence of conflicts. On average, both parents' and adolescents' use of positive conflict resolution tends to increase, and negative conflict resolution tends to decrease, with age, although ...
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