Results 91 to 100 of about 584,540 (386)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Influence of hydraulic resistance on flow features in an open channel confluence [PDF]

, 2014
A numerical model based on the 3D shallow water equations is set up for a 90° angle open channel confluence. The model is first calibrated and validated using experimental data by (Shumate, 1998).
Creëlle, Stéphan, De Mulder, Tom, Schindfessel, Laurent, Van Oyen, Tomas   +3 more
core  

Confluence reduction for Markov automata [PDF]

, 2013
Markov automata are a novel formalism for specifying systems exhibiting nondeterminism, probabilistic choices and Markovian rates. Recently, the process algebra MAPA was introduced to efficiently model such systems.
A. Hartmanns, A. Valmari, C. Eisentraut, D. Guck, D. Peled, H. Boudali, M. Ajmone Marsan, M. Bozzano, M. Timmer, M. Timmer, P. Godefroid, S.C.C. Blom, Y. Deng   +12 more
core   +8 more sources

Effect of the Junction Angle on Turbulent Flow at a Hydraulic Confluence

, 2018
Despite the existing knowledge concerning the hydrodynamic processes at river junctions, there is still a lack of information regarding the particular case of low width and discharge ratios, which are the typical conditions of mountain river confluences.
N. Penna, M. Marchis, O. Canelas, E. Napoli, A. Cardoso, R. Gaudio   +5 more
semanticscholar   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Denz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

The Unreliable Narrator as a Precedent to the Post-Truth Era: Subjective Personal Memory in the Literary Autobiographies of Eudora Welty and Tom Robbins [PDF]

University of Bucharest Review. Literary and Cultural Studies Series, 2019
Trying to find the roots of the current post-truth era, one possible path of origin presents itself when it comes to the literary tradition: the unreliable narrator.
Dorotka Bachratá
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

“Many Rivers to Cross:” Orphic Confluences of Fred D’Aguiar’s Children of Paradise and Wilson Harris’ Palace of the Peacock

Angles, 2018
Seldom does criticism address cross-cultural issues in terms of confluence. In fact, scholars tend to use chaos theory (Glissant, Benitez-Rojo), oceanic tropes (Gilroy, Brathwaite), and linguistic foci (Chamoiseau, Bhabha) to deal with them.
Léo Courbot
doaj   +1 more source

Influence of junction angle on three-dimensional flow structure and bed morphology at confluent meander bends during different hydrological conditions [PDF]

, 2014
© 2014 John Wiley & Sons, Ltd. Recent field and modeling investigations have examined the fluvial dynamics of confluent meander bends where a straight tributary channel enters a meandering river at the apex of a bend with a 90° junction angle.
Abrahams, Abrahams, Ashmore, Best, Best, Best, Best, Best, Best, Best, Biron, Biron, Biron, Biron, Boyer, Bradbrook, Bradbrook, Bradbrook, Bristow, Callaway, Constantinescu, Davis, DeSerres, Dietrich, Dinehart, Dinehart, Dordević, Flint, Kenworthy, Kleinhans, Lane, Lane, Mackay, McLelland, McLelland, Mosley, Muste, Parsons, Parsons, Parsons, Parsons, Rhoads, Rhoads, Rhoads, Rhoads, Rhoads, Rhoads, Richardson, Riley, Roy, Roy, Stallard, Szupiany, Szupiany, Weerakoon, Zinger, Zinger   +56 more
core   +1 more source

Stratification Effects on Flow Hydrodynamics and Mixing at a Confluence With a Highly Discordant Bed and a Relatively Low Velocity Ratio

Water Resources Research, 2018
The effects of temperature induced stratification on flow hydrodynamics, thermal mixing, and the capacity of the flow to entrain sediment at a medium‐size stream confluence with a highly discordant bed are investigated.
Zhen Cheng, G. Constantinescu
semanticscholar   +1 more source