Results 91 to 100 of about 552,801 (329)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Japanese Modernism And Cine-Text : Fragments And Flows At Empire\u27s Edge In Kitagawa Fuyuhiko And Yokomitsu Riichi [PDF]

open access: yes, 2012
This article notes that Kitagawa Fuyuhiko\u27s writings from the 1920s and 1930s, together with the contemporaneous works of prose author Yokomitsu Riichi, are strongly marked by the confluence of the literary and the cinematic.
Gardner, William O.
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Biological report - fish mortality, River Conder, 21.7.79 [PDF]

open access: yes, 1979
Following a large scale fish mortality caused by a considerable spillage of a pentachlbrophenol-based disinfectant from a mushroom farm, a biological survey of the river Conder was undertaken on 23.7.79.
Ingersent, B.
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Numerical Simulation of Flow and Scour in a Laboratory Junction

open access: yesGeosciences, 2018
Confluences are a common feature of riverine systems; the area of converging flow streamlines and potential mixing of separate flows. The hydrodynamics about confluences have a highly complex three-dimensional flow structure.
Javad Ahadiyan   +3 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Partial monoids: associativity and confluence [PDF]

open access: yes, 2010
A partial monoid $P$ is a set with a partial multiplication $\times$ (and total identity $1_P$) which satisfies some associativity axiom. The partial monoid $P$ may be embedded in a free monoid $P^*$ and the product $\star$ is simulated by a string ...
Duchamp, Gérard   +2 more
core   +2 more sources

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