Results 71 to 80 of about 604,405 (322)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Effect of bed roughness on the mixing layers in a 90° asymmetrical confluence [PDF]
, 2015 In this paper, the mixing layer between the two incoming flows in a 90 degree, asymmetrical open channel confluence is investigated. Specific attention is given towards looking into the effect of bed roughness on the flow patterns in the confluence. This
Creëlle, Stéphan +2 more
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Decreasing Diagrams for Confluence and Commutation
, 2020 Like termination, confluence is a central property of rewrite systems. Unlike for termination, however, there exists no known complexity hierarchy for confluence.
Endrullis, Jörg +2 more
core +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Influence of hydraulic resistance on flow features in an open channel confluence [PDF]
, 2014 A numerical model based on the 3D shallow water equations is set up for a 90° angle open channel confluence. The model is first calibrated and validated using experimental data by (Shumate, 1998).
Creëlle, Stéphan +3 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The Unreliable Narrator as a Precedent to the Post-Truth Era: Subjective Personal Memory in the Literary Autobiographies of Eudora Welty and Tom Robbins [PDF]
University of Bucharest Review. Literary and Cultural Studies Series, 2019 Trying to find the roots of the current post-truth era, one possible path of origin presents itself when it comes to the literary tradition: the unreliable narrator.
Dorotka Bachratá
doaj +1 more source
Contaminants in Unionid Mussels from the Confluence of the Mississippi and Illinois Rivers [PDF]
, 2008 Unionid mussels were collected from three mussel beds near the confluence of the Mississippi and Illinois rivers in 2003 to evaluate concentrations of selected elements and organic compounds in three abundant species and to preliminarily investigate the ...
Esarey, Joan +5 more
core