Confluence of the right internal iliac vein into a compressed left common iliac vein [PDF]
, 2015 The authors describe the abnormal confluence of the right internal iliac vein into a left common iliac vein compressed by the overlying right common iliac artery.
Amore, Miguel +2 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
La convergence des destins chez Thomas Hardy
Cahiers Victoriens et Edouardiens, 2019 In the diegesis of Hardy’s novels, when movements converge to a centre, it means that we are approaching ‘the central place’, ‘the intimate exteriority or “extimacy”’ which Lacan calls the Thing (Lacan 2008, 171). It means that the subject (i.e.
Annie Ramel
doaj +1 more source
The language of Stratified Sets is confluent and strongly normalising [PDF]
, 2018 We study the properties of the language of Stratified Sets (first-order logic with $\in$ and a stratification condition) as used in TST, TZT, and (with stratifiability instead of stratification) in Quine's NF.
Gabbay, Murdoch J.
core +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Confluence versus Ample Sets in Probabilistic Branching Time [PDF]
, 2011 To improve the efficiency of model checking in general, and probabilistic model checking in particular, several reduction techniques have been introduced. Two of these, confluence reduction and partial-order reduction by means of ample sets, are based on
Hansen, Henri, Timmer, Mark
core +2 more sources
A Particular Solution of a Painlev\'e System in Terms of the Hypergeometric Function ${}_{n+1}F_n$ [PDF]
, 2010 In a recent work, we proposed the coupled Painlev\'e VI system with $A^{(1)}_{2n+1}$-symmetry, which is a higher order generalization of the sixth Painlev\'e equation ($P_{\rm VI}$).
Suzuki, Takao
core +5 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Three models for gene assembly in ciliates: a comparison [PDF]
Computer Science Journal of Moldova, 2010 We survey in this paper the main differences among three variants of an intramolecular model for gene assembly: the general, the simple, and the elementary models.
Miika Langille +2 more
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