Results 71 to 80 of about 552,801 (329)

Solution of the two identical ion Penning trap final state [PDF]

open access: yes, 2001
We have derived a closed form analytic expression for the asymptotic motion of a pair of identical ions in a high precision Penning trap. The analytic solution includes the effects of special relativity and the Coulomb interaction between the ions.
B. Moyers   +11 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Lateral asymmetry in the hippocampal response to the remoteness of autobiographical memories [PDF]

open access: yes, 2003
The time scale of hippocampal involvement in retrieving memories, particularly those more remote, is still a matter of debate. Some propose that the hippocampus is not involved in the retrieval of remote memories, whereas others assert that it is ...
Frith, C.D., Maguire, E.A.
core  

Confluence of hypergeometric functions and integrable hydrodynamic type systems

open access: yes, 2016
It is known that a large class of integrable hydrodynamic type systems can be constructed through the Lauricella function, a generalization of the classical Gauss hypergeometric function. In this paper, we construct novel class of integrable hydrodynamic
Kodama, Y., Konopelchenko, B.
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Disparition du delta intérieur du Drac et naissance de la presqu’île grenobloise : signature de la fin du Petit Age Glaciaire

open access: yesCybergeo, 2017
From a wide variety of maps and iconographic sources, spatially corrected and georeferenced, this work seeks to precisely reconstruct the hydro-morphological changes at the confluence of two main Alpine rivers: Drac and Isère.
Dominique Dumas, Adrien Favillier
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Au confluent exactement : Deadlock (1921), Revolving Lights (1923) et The Trap (1925) de Dorothy Richardson

open access: yesÉtudes Britanniques Contemporaines, 2017
The word ‘confluence’ refers both to the place where two or more rivers meet and the fact that they start to flow together. This term is particularly apt to capture some of the paradoxes that characterize the three following chapters of Pilgrimage ...
Florence Marie
doaj   +1 more source

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