Results 81 to 90 of about 545,156 (279)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Introduction: Trying to Define Literature’s Confluences

Études Britanniques Contemporaines, 2017
Previous issues of Études britanniques contemporaines chose to focus on the agonistic dynamics of British literature and the arts. The present issue explores a paradigm which has hitherto received very little critical attention. The notion of ‘confluence’
Catherine Bernard
doaj   +1 more source

Characterizing PSPACE with Shallow Non-Confluent P Systems [PDF]

, 2018
In P systems with active membranes, the question of understanding the power of non-confluence within a polynomial time bound is still an open problem.
Leporati, Alberto, Manzoni, Luca, Mauri, Giancarlo, Porreca, Antonio E., Zandron, Claudio   +4 more
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Circumferential endoscopic submucosal dissection of distal rectal polyp in a patient with portal hypertension complicated by bowel obstruction

VideoGIE, 2023
Siddharth B. Javia, MD, Whitney Reid, DO, Jennifer Jorgensen, MD   +2 more
doaj   +1 more source

Au confluent exactement : Deadlock (1921), Revolving Lights (1923) et The Trap (1925) de Dorothy Richardson

Études Britanniques Contemporaines, 2017
The word ‘confluence’ refers both to the place where two or more rivers meet and the fact that they start to flow together. This term is particularly apt to capture some of the paradoxes that characterize the three following chapters of Pilgrimage ...
Florence Marie
doaj   +1 more source

Partial monoids: associativity and confluence [PDF]

, 2010
A partial monoid $P$ is a set with a partial multiplication $\times$ (and total identity $1_P$) which satisfies some associativity axiom. The partial monoid $P$ may be embedded in a free monoid $P^*$ and the product $\star$ is simulated by a string ...
Duchamp, Gérard, Poinsot, Laurent, Tollu, Christophe   +2 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Hydrodynamic Response of Channel Flow Confluence to the Tributary Floodplain Topography

Water Resources Research
River confluences with a compound‐channel tributary are common in large river networks, for example, the Yangtze River basin and the Amazon basin. They affect the confluence hydrodynamics, nutrient depletion and fish migration in the network, due to the ...
Guanghui Yan, Saiyu Yuan, Hongwu Tang, Dong Xu, Mengyang Liu, Colin Whittaker, Carlo Gualtieri   +6 more
doaj   +1 more source