Results 101 to 110 of about 739,261 (262)

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Enhanced chitosan fibres for skin regeneration: solution blow spinning and incorporation with platelet lysate and tannic acid

Materials Research Express
In this study, we developed and characterised enhanced chitosan/polyethylene oxide (PEO) nanofibre scaffolds using solution blow spinning (SBS) for potential application in skin tissue engineering.
Håvard J Haugen, David Coelho, Nguyen D Tien, Tianxiang Geng, Jonny J Blaker   +4 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

confocal dataset

, 2019
Confocal image z stack of ciliated airway epithelial cells infected with influenza Pr8 for ...
Claire Smith (6424490)
core   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Dual confocal laser-induced fluorescence/moveable contactless

, 2009
A new dual simultaneous detector was developed for capillary electrophoresis microchip. Confocal laser-induced fluorescence (LIF) and moveable contactless conductivity detection (MCCD) were combined together for the first time.
申峰, 康琦, 杨萌, 于泳, Yong Yu
core  

Confocal Microscopy.

, 2014
Shows the cellular uptake of ATV-BSA nanoparticles by MiaPaCa-2 cells using confocal microscopy.
Aswathy Ravindran (518851), George Priya Doss. C (518850), Anjali. C. H (518849), Rajith B (205496), Sripriyalakshmi. S (518848)   +4 more
core   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Confocal cardiomyocyte sub-cellular measurements.

, 2019
Confocal cardiomyocyte sub-cellular measurements.
Timothy L. M. Jones (6569954), Anthony J. Hickey (388291), Amelia S. Power (6569951), Marie-Louise Ward (5576849), Ruth Norman (841390)   +4 more
core   +1 more source

Detection of Magnetic Field Effects by Confocal Microscopy: Data

, 2020
This dataset contains raw data and accompanying analysis used in the publication 'Detection of Magnetic Field Effects by Confocal Microscopy' by Dejean et al. The data was recorded using a Zeiss inverted confocal microscope - Exciter 5.
Konowalczyk, Marcin, Déjean, Victoire, Timmel, Christiane   +2 more
core   +1 more source