Results 1 to 10 of about 9,005 (169)
MethodsX, 2023 Microneedle patches have been widely used in a minimally invasive manner for various drug delivery applications. However, for developing these microneedle patches, master molds are required, which are generally made of metal and are very expensive.
Mamatha M. Pillai +2 more
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Sharp-wave ripple doublets induce complex dendritic spikes in parvalbumin interneurons in vivo
Nature Communications, 2022 The influence of sharp-wave ripples (SPW-Rs) on dendritic computation remains poorly understood. Here, the authors demonstrate the existence of SPW-R associated, branch-specific, dendritic spikes which serve as a temporal and spatial coincidence ...
Linda Judák +18 more
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An open-source pipeline for analysing changes in microglial morphology
Open Biology, 2021 Changes in microglial morphology are powerful indicators of the inflammatory state of the brain. Here, we provide an open-source microglia morphology analysis pipeline that first cleans and registers images of microglia, before extracting 62 parameters ...
Devin Clarke +2 more
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3D optogenetic control of arteriole diameter in vivo
eLife, 2022 Modulation of brain arteriole diameter is critical for maintaining cerebral blood pressure and controlling regional hyperemia during neural activity. However, studies of hemodynamic function in health and disease have lacked a method to control arteriole
Philip J O'Herron +4 more
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Quantitative analysis of 1300-nm three-photon calcium imaging in the mouse brain
eLife, 2020 1300 nm three-photon calcium imaging has emerged as a useful technique to allow calcium imaging in deep brain regions. Application to large-scale neural activity imaging entails a careful balance between recording fidelity and perturbation to the sample.
Tianyu Wang +8 more
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Frontiers in Synaptic Neuroscience, 2020 In the vertebrate olfactory bulb (OB), axonless granule cells (GC) mediate self- and lateral inhibitory interactions between mitral/tufted cells via reciprocal dendrodendritic synapses.
Tiffany Ona Jodar +6 more
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Nanomaterials, 2021 The performance of quasi-spherical gold nanoparticles (GNPs) on the generation of reactive oxygen species (ROS) to cause cell damage, as irradiated by a two-photon laser, is studied.
Jiunn-Woei Liaw +2 more
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The cell adhesion molecule Sdk1 shapes assembly of a retinal circuit that detects localized edges
eLife, 2021 Nearly 50 different mouse retinal ganglion cell (RGC) types sample the visual scene for distinct features. RGC feature selectivity arises from their synapses with a specific subset of amacrine (AC) and bipolar cell (BC) types, but how RGC dendrites ...
Pierre-Luc Rochon +3 more
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Two-photon polymerization for 3D biomedical scaffolds: Overview and updates
Frontiers in Bioengineering and Biotechnology, 2022 The needs for high-resolution, well-defined and complex 3D microstructures in diverse fields call for the rapid development of novel 3D microfabrication techniques.
Xian Jing +4 more
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Polarization-controlled anisotropy in hybrid plasmonic nanoparticles
Nanophotonics, 2022 Anisotropy has played a critical role in many material systems, but its controllable creation and modulation have been a long-lasting challenge for the scientific communities. Polarization-addressed anisotropy appears more attractive among all approaches
Wang Xujie +7 more
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