Results 31 to 40 of about 250,736 (266)

Improving Focal Photostimulation of Cortical Neurons with Pre-derived Wavefront Correction

open access: yesFrontiers in Cellular Neuroscience, 2017
Recent progress in neuroscience to image and investigate brain function has been made possible by impressive developments in optogenetic and opto-molecular tools.
Vincent R. Daria   +6 more
doaj   +1 more source

Multimodal Characterization of Seizures in Zebrafish Larvae

open access: yesBiomedicines, 2022
Epilepsy accounts for a significant proportion of the world’s disease burden. Indeed, many research efforts are produced both to investigate the basic mechanism ruling its genesis and to find more effective therapies.
Lapo Turrini   +6 more
doaj   +1 more source

A New Two-Photon Ratiometric Fluorescent Probe for Detecting Alkaline Phosphatase in Living Cells

open access: yesMolecules, 2016
Alkaline phosphatase (ALP) is an important diagnostic indicator of many human diseases. To quantitatively track ALP in biosystems, herein, for the first time, we report an efficient two-photon ratiometric fluorescent probe, termed probe 1 and based on ...
Xiaohong Zhou   +3 more
doaj   +1 more source

Two-photon absorption and two-photon-induced isomerization of azobenzene compounds

open access: yesRSC Advances, 2020
The process of two-photon-induced isomerization occurring in various organic molecules, among which azobenzene derivatives hold a prominent position, offers a wide range of functionalities, which can be used in both material and life sciences.
Marta Dudek   +5 more
openaire   +3 more sources

Neutralino annihilation into two photons [PDF]

open access: yesPhysics Letters B, 1997
We compute the annihilation cross-section of two neutralinos at rest into two photons, which is of importance for the indirect detection of neutralino dark matter in the galactic halo through a quasi-monochromatic gamma-ray line. We include all diagrams to one-loop level in the minimal supersymmetric extension of the standard model. We use the helicity
Bern, Z., Gondolo, P., Perelstein, M.
openaire   +2 more sources

RETRACTED: An acridone-derived fluorescent off-on probe for detection and in vivo imaging of nitroreductase

open access: yesFrontiers in Materials, 2023
Understanding the functions of enzymes in various physiological processes is important, but the design of signaling probes for fast analysis of enzymatic activity is particularly challenging.
Meicen Liu   +11 more
doaj   +1 more source

Simultaneous two-photon imaging and two-photon optogenetics of cortical circuits in three dimensions

open access: yeseLife, 2018
The simultaneous imaging and manipulating of neural activity could enable the functional dissection of neural circuits. Here we have combined two-photon optogenetics with simultaneous volumetric two-photon calcium imaging to measure and manipulate neural
Weijian Yang   +4 more
doaj   +1 more source

Multi-neuronal recording in unrestrained animals with all acousto-optic random-access line-scanning two-photon microscopy

open access: yesFrontiers in Neuroscience, 2023
To understand how neural activity encodes and coordinates behavior, it is desirable to record multi-neuronal activity in freely behaving animals. Imaging in unrestrained animals is challenging, especially for those, like larval Drosophila melanogaster ...
Akihiro Yamaguchi   +7 more
doaj   +1 more source

Chemical Two-Photon Fluorescence

open access: yesAnalytical Chemistry, 2015
We describe a method based on a caged fluorescent molecule that can act as a chemical two-photon probe. It is composed of an organic fluorophore and a ruthenium-bipyridine complex that acts as a photoremovable quencher. For the fluorophore to be emissive, two independent photons must act on the molecule: the first photon frees the fluorescent ligand ...
Carrone, Guillermo Alejandro   +1 more
openaire   +3 more sources

Reliable and Elastic Propagation of Cortical Seizures In Vivo

open access: yesCell Reports, 2017
Mapping the fine-scale neural activity that underlies epilepsy is key to identifying potential control targets of this frequently intractable disease.
Michael Wenzel   +3 more
doaj   +1 more source

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