Results 11 to 20 of about 250,736 (266)

Two‐Photon Absorption and the Design of Two‐Photon Dyes

open access: yesAngewandte Chemie - International Edition, 2009
AbstractTwo photons are better than one: This principle applies to a wide range of applications, ranging from engineering to physiology. Recent advances in our understanding of the phenomenon of two‐photon absorption (see picture) and in the design of two‐photon dyes are rapidly increasing the scope of this field.magnified imageTwo‐photon absorption ...
Miłosz Pawlicki   +2 more
exaly   +3 more sources

Molecular engineering of individual dye-based nanoparticle photostability for ultrabright two-photon fluorescence. [PDF]

open access: yesBeilstein J Nanotechnol
Dye-based fluorescent organic nanoparticles (dFONs) represent a promising class of bioimaging probes combining high brightness with molecular tunability.
Kurek E   +6 more
europepmc   +2 more sources

Two-photon polymerization based reusable master template to fabricate polymer microneedles for drug delivery

open access: yesMethodsX, 2023
Microneedle patches have been widely used in a minimally invasive manner for various drug delivery applications. However, for developing these microneedle patches, master molds are required, which are generally made of metal and are very expensive.
Mamatha M. Pillai   +2 more
doaj   +1 more source

Sharp-wave ripple doublets induce complex dendritic spikes in parvalbumin interneurons in vivo

open access: yesNature Communications, 2022
The influence of sharp-wave ripples (SPW-Rs) on dendritic computation remains poorly understood. Here, the authors demonstrate the existence of SPW-R associated, branch-specific, dendritic spikes which serve as a temporal and spatial coincidence ...
Linda Judák   +18 more
doaj   +1 more source

An open-source pipeline for analysing changes in microglial morphology

open access: yesOpen Biology, 2021
Changes in microglial morphology are powerful indicators of the inflammatory state of the brain. Here, we provide an open-source microglia morphology analysis pipeline that first cleans and registers images of microglia, before extracting 62 parameters ...
Devin Clarke   +2 more
doaj   +1 more source

3D optogenetic control of arteriole diameter in vivo

open access: yeseLife, 2022
Modulation of brain arteriole diameter is critical for maintaining cerebral blood pressure and controlling regional hyperemia during neural activity. However, studies of hemodynamic function in health and disease have lacked a method to control arteriole
Philip J O'Herron   +4 more
doaj   +1 more source

Quantitative analysis of 1300-nm three-photon calcium imaging in the mouse brain

open access: yeseLife, 2020
1300 nm three-photon calcium imaging has emerged as a useful technique to allow calcium imaging in deep brain regions. Application to large-scale neural activity imaging entails a careful balance between recording fidelity and perturbation to the sample.
Tianyu Wang   +8 more
doaj   +1 more source

Local Postsynaptic Signaling on Slow Time Scales in Reciprocal Olfactory Bulb Granule Cell Spines Matches Asynchronous Release

open access: yesFrontiers in Synaptic Neuroscience, 2020
In the vertebrate olfactory bulb (OB), axonless granule cells (GC) mediate self- and lateral inhibitory interactions between mitral/tufted cells via reciprocal dendrodendritic synapses.
Tiffany Ona Jodar   +6 more
doaj   +1 more source

The Effect of Quasi-Spherical Gold Nanoparticles on Two-Photon Induced Reactive Oxygen Species for Cell Damage

open access: yesNanomaterials, 2021
The performance of quasi-spherical gold nanoparticles (GNPs) on the generation of reactive oxygen species (ROS) to cause cell damage, as irradiated by a two-photon laser, is studied.
Jiunn-Woei Liaw   +2 more
doaj   +1 more source

Multipath Entanglement of Two Photons [PDF]

open access: yesPhysical Review Letters, 2009
We present a novel optical device based on an integrated system of micro-lenses and single mode optical fibers. It allows to collect and direct into many modes two photons generated by spontaneous parametric down conversion. By this device multiqubit entangled states and/or multilevel qu-$d$it states of two photons, encoded in the longitudinal momentum
ROSSI A   +4 more
openaire   +6 more sources

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