Results 91 to 100 of about 31,204 (291)

Crystal Facet‐Polysaccharide Matching in CFS‐P Nanocrystals Drives Fungal Uptake, Vacuole Destruction, and Selective Antifungal Activity

Advanced Science, EarlyView.
Facet‐engineered PVP‐capped CuFeSe2 nanocrystals exhibit potent, selective antifungal activity by strongly binding cell‐wall mannan, enabling vacuolar entry and organelle disruption. High‐index facets show superior mannan affinity, validated by theoretical calculations and experiments. CFS‐P induces vacuolar cavitation, mitochondrial abnormalities, and
Zhaohui Wang, Xiaojin Deng, Xujuan Huang, Yuhang Pan, Yao Qin, Lu Zhang, Le Xu, Tianyi Qin, Deteng Zhang, Yi Ma, Yalong Wang   +10 more
wiley   +1 more source

Three-Dimensional Structure of Biofilm Formed on Glass Surfaces Revealed Using Scanning Ion Conductance Microscopy Combined with Confocal Laser Scanning Microscopy

Microorganisms
Biofilms cause a variety of problems, such as food spoilage, food poisoning, infection, tooth decay, periodontal disease, and metal corrosion, so knowledge on biofilm prevention and removal is important.
Nobumitsu Hirai, Yuhei Miwa, Shunta Hattori, Hideyuki Kanematsu, Akiko Ogawa, Futoshi Iwata   +5 more
doaj   +1 more source

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

Advanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi, Jingrui Cao, Tong Wu, Guang Yang, YaWen Yang, Shixin Zhang, Wenwen Su, Hongyu Chu, Yangyang Zhao, Shan Jiang, Qiong Wu, Dongxu Jiao, Fangfang Chen   +12 more
wiley   +1 more source

Reconstruction and regularization approaches for photon-resolved image scanning microscopy [PDF]

EPJ Web of Conferences
Fast, sensitive detector arrays make Image Scanning Microscopy (ISM) a natural successor to confocal laser scanning microscopy (CLSM), enabling super-resolution (SR) with excellent signal-to-noise ratio (SNR).
Garrè Giacomo, Zunino Alessandro, Vicidomini Giuseppe   +2 more
doaj   +1 more source

Confocal laser scanning microscopy—a powerful tool in bone research

, 2018
The confocal laser scanning microscope (CLSM) enables the collection of images picturing selected planes in depth of thick samples, thus giving 3D information while keeping the sample intact.
Silvia Spitzer, Spitzer, S., Klaus Klaushofer, Barbara Misof, Franz Varga, Roschger, A., Klaushofer, K., Andreas Roschger, Misof, B., Paul Roschger, Varga, F., Stéphane Blouin, Blouin, S., Roschger, P.   +13 more
core   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source

A One-step Hydrothermal Method of Nitrogen-doped Graphene Quantum Dots Decorated Graphene for Fabrication of Paper-based Fluorescent Composite

BioResources, 2016
A facile approach for producing fluorescent composite paper containing nitrogen-doped graphene quantum dots (N-GQDs) and graphene on the surface of the modified fibers was implemented from the exfoliation of graphite oxide (GO) using a one-step ...
Yu Bian, Beihai He, Junrong Li
doaj   +1 more source

Confocal laser scanning microscopy (CLSM) study of hepatocytes cultured on collagen films and gels [PDF]

, 2002
Summary of paper describing the process whereby primary hepatocyte cultures form an integral part of many hybrid artificial liver designs, and the extracellular matrix environment of the cultures is an important factor for optimal expression of hepatocyte-specific phenotype. This study investigates the effect of incorporating 20% chondroitin-6-sulphate
Kataropoulou, M., Goldie, E., Connel, G., Grant, M.H.   +3 more
openaire   +1 more source

Confocal laser scanning microscopy. Using new technology to answer old questions in forensic investigations.

, 2008
Confocal laser scanning microscopy (CLSM) is a relatively new technique for microscopic imaging. It has found a wide field of application in the general sphere of biological sciences.
NERI, MARGHERITA, Karch SB, Fineschi V., Riezzo I, RIEZZO, IRENE, POMARA, CRISTOFORO, Turillazzi E, Pomara C, TURILLAZZI, EMANUELA   +8 more
core   +1 more source

Nanoscale Secondary Ion Mass Spectrometry for Quantifying Membrane Fouling: Fouling Layer Structure and Chemical Interaction

Advanced Science, EarlyView.
Nanoscale secondary ion mass spectrometry (Nano SIMS) is established as a powerful analytical tool to visualize and quantify the membrane fouling layers. ABSTRACT Membrane technology has garnered considerable attention for applications in wastewater treatment and resource recovery. Nevertheless, membrane fouling remains a major barrier, yet the lack of
Mengfei Wu, Xinhua Wang, Pin Zhao, Weilong Song, Ming Xie   +4 more
wiley   +1 more source