Results 81 to 90 of about 2,617,420 (275)

The Application of Confocal Laser Scanning Microscopy in Investigating the Correlation between Microstructure and Function in Whole Grain Foods

Liang you shipin ke-ji
Confocal laser scanning microscopy (CLSM)，through the use of fluorescent probes for labeling, enables the visualization of the spatial distribution of components in whole grain foods and the in situ characterization of their microstructure, and has ...
GAO Kun, TAN Bin
doaj   +1 more source

Deciphering the distribution of organic components in brachiopod shells by confocal laser scanning microscopy

, 2008
Summary Characterization of the nature and distribution of organic components is crucial to understand shell formation in marine invertebrates. Although several techniques can provide detailed information at high spatial resolution, few of them are non ...
Perez-Huerta, A., Williams, C.T., Mackay, S., Pérez-Huerta, Alberto, Cusack, M., Cusack, Maggie, Ball, Alexander, Williams, C Terry, Mackay, Seonaid, Ball, A.   +9 more
core   +1 more source

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

Advanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang, Yuhang Tang, Ronghao Yue, Jingtao Xu, Yong Tao, Jie Chen, Shipeng Li, Guosheng Zhao, Jinfang Xue, Mingwei Sun, Fenglei Gao, Yunsheng Ou, Yang Wang   +12 more
wiley   +1 more source

Ultrablack color in velvet ant cuticle

Beilstein Journal of Nanotechnology
We studied the ultrastructure of the ultrablack cuticle in Traumatomutilla bifurca, an enigmatic and visually striking species of velvet ants (Hymenoptera, Mutillidae).
Vinicius Marques Lopez, Wencke Krings, Juliana Reis Machado, Stanislav Gorb, Rhainer Guillermo-Ferreira   +4 more
doaj   +1 more source

Long‐Chain Molecule Reconstruction of Novel Solvation Structure to Stabilize Zinc Metal Anode

Advanced Science, EarlyView.
Triethylene glycol diacetate (TGD), with unique long‐chain characteristics and rich oxygen‐containing functional groups, was used as an electrolyte additive to reconstruct the solvation structure. TGD can reduce the erosion of H2O molecules on the Zn anode, effectively homogenize the electric field distribution. Therefore, the Zn//Zn symmetric cell can
Changdong Chen, Lingwei Xue, Gaojie Li, Xueli Chen, Yongjun Han, Liwei Mi, Yuqing Chen   +6 more
wiley   +1 more source

Investigations of Dye-Sensitised Titania Solar Cell Electrode Using Confocal Laser Scanning Microscopy [PDF]

, 2003
We have characterised a dye-sensitised nanoporous nanocrystalline titania film used in prototype photoelectrochemical solar cell production. The film was sensitised with two types of ruthenium (II) based dyes for different times, between 0.5 and 24 ...
Tesfamichael, Tuquabo, Bostrom, Thor E., Will, Geoffrey D., Bell, John M.   +3 more
core   +1 more source

A Single‐Amino‐Acid Ligand for LAT1: A Minimalist and Modular Platform for Lysosome‐Targeted Degradation of Membrane Proteins

Advanced Science, EarlyView.
LA‐LYTAC repurposes the cancer‐enriched amino acid transporter LAT1 as a lysosomal trafficking receptor for targeted membrane‐protein degradation. A single phenylalanine‐derived ligand, modularly linked to antibodies or small‐molecule binders, recruits PD‐L1, EGFR, or integrins to LAT1, triggering transporter‐mediated internalization, lysosomal ...
Liquan Zhu, Ke Liu, Haotian Liu, Chaoqi He, Xiaozhen Liu, Xin Zeng, Misha Mao, Yuxiao Mu, Ying Li, Qinghui Zheng, Hongchao Tang, Da Qian, Xuli Meng   +12 more
wiley   +1 more source

Three-Dimensional Structure of Biofilm Formed on Glass Surfaces Revealed Using Scanning Ion Conductance Microscopy Combined with Confocal Laser Scanning Microscopy

Microorganisms
Biofilms cause a variety of problems, such as food spoilage, food poisoning, infection, tooth decay, periodontal disease, and metal corrosion, so knowledge on biofilm prevention and removal is important.
Nobumitsu Hirai, Yuhei Miwa, Shunta Hattori, Hideyuki Kanematsu, Akiko Ogawa, Futoshi Iwata   +5 more
doaj   +1 more source

Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy

Advanced Science, EarlyView.
A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan, Xuan Liu, Qian‐Fang Meng, Lei Cao, Rongrong Li, Yangtao Xu, Jing Zhang, Chenchen Zhao, Lang Rao, Chen Yu   +9 more
wiley   +1 more source

Synergistic p53 Pathway Activation Through Sono‐Gene Therapy Induced by Ultrasound‐Triggered Theranostic Mesoporous Nanoparticles

Advanced Science, EarlyView.
Schematic representation of ultrasound‐mediated ICG/siCD24@MSN‐LCD from nanostructure to synergistic sono‐gene therapy. This nanoplatform targets ASGPR via the LCD shell, which dissociates to release loaded ICG and siCD24. The core mechanism involves ultrasound‐guided sonodynamic therapy by ICG and CD24 knockdown by siCD24, both activating the p53 axis
Yading Zhao, Lu Guo, Dandan Shi, Xiao Sun, Mengmeng Shang, Song Ning, Shuting Huang, Xiaoxuan Wang, Rui Liu, Yuye Fu, Suyun Li, Jie Li   +11 more
wiley   +1 more source