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Three-Dimensional Digital Confocal Raman Microscopy
Applied Spectroscopy, 1993We describe an iterative image restoration technique which functions as digital confocal microscopy for Raman images. We deconvolute the lateral and axial components of the microscope point spread function from a series of optical sections, to generate a stack of well-resolved Raman images which describe the three-dimensional topology of a sample. The
Anurag Govil +2 more
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High-resolution confocal Raman microscopy using pixel reassignment
Optics Letters, 2016We present a practical modification of fiber-coupled confocal Raman scanning microscopes that is able to provide high confocal resolution in conjunction with high light collection efficiency. For this purpose, the single detection fiber is replaced by a hexagonal lenslet array in combination with a hexagonally packed round-to-linear multimode fiber ...
Clemens, Roider +2 more
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Confocal Raman microscopy: common errors and artefacts
The Analyst, 2010Confocal Raman microscopy is a powerful tool for research and analysis in the chemical, materials and life sciences, particularly for non-destructive depth profiling of transparent systems. Unfortunately, many Raman microscopes are not optimally configured for this purpose, and so yield unnecessarily low signal-to-noise spectra with poor spatial ...
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Imaging theory of nonlinear Raman confocal microscopy
Journal of Modern Optics, 2008A novel nonlinear Raman confocal microscopy utilizing Raman induced Kerr effect spectroscopy (RIKES) is presented in this paper. The imaging theory of RIKES confocal microscopy with Gaussian beam is derived. The imaging properties of RIKES confocal microscopy and the impact of different beam waist widths of Gaussian beam on the lateral and axial ...
L.N. Guo, Z.L. Tang, D. Xing
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Confocal Raman Microscopy in Pharmaceutical Development
2010There is a wide range of applications of confocal Raman microscopy in pharmaceutical development. It is a powerful tool to probe the distribution of components within a formulation, to characterize homogeneity of pharmaceutical samples, to determine solid state of drug substances and excipients as well as to characterize contaminations and foreign ...
Thomas F. Haefele, Kurt Paulus
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Polarized Raman Confocal Microscopy of Single Gallium Nitride Nanowires
Journal of the American Chemical Society, 2005Polarized Raman spectra and corresponding Raman scattering intensity images of an isolated gallium nitride nanowire with a diameter of 170 nm are presented. The sensitivity of the confocal microscope combined with a high-resolution piezoelectric stage enables analysis of the crystalline phase and crystallographic orientation of an individual nanowire ...
Pauzauskie P.J. +4 more
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Imaging of plant cell walls by confocal Raman microscopy
Nature Protocols, 2012Raman imaging of plant cell walls represents a nondestructive technique that can provide insights into chemical composition in context with structure at the micrometer level (
Gierlinger, Notburga, N. +2 more
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Confocal Raman Microscopy of Protein Adsorbed in Chromatographic Particles
Analytical Chemistry, 2012Confocal Raman microscopy is a nondestructive analytical technique that combines the chemical information from vibrational spectroscopy with the spatial resolution of confocal microscopy. It was applied, for the first time, to measure conformation and distribution of protein adsorbed in wetted chromatographic particles.
Yuewu, Xiao +4 more
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Confocal Raman Microscopy of Optical-Trapped Particles in Liquids
Annual Review of Analytical Chemistry, 2010The in situ analysis of small, dispersed particles in liquids is a challenging problem, the successful solution to which influences diverse applications of colloidal particles in materials science, synthetic chemistry, and molecular biology. Optical trapping of small particles with a tightly focused laser beam can be combined with confocal Raman ...
Daniel P, Cherney, Joel M, Harris
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Confocal Raman microscopy of supercritical fluid dyeing of polymers
The Analyst, 2003Supercritical CO2 was used as a medium to introduce azo-dyes into polymers (PMMA and PET). Confocal Raman microscopy has been applied using dry metallurgical and oil objectives to measure the concentration of dye as a function of distance from the surface to the core of the polymer samples.
Kazarian, SG, Chan, KLA
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