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Probing Chirality of a Lipid Tubular by Confocal Raman Microscopy
Journal of Nanoscience and Nanotechnology, 2010The chiral phospholipids 1,2-bis-(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine (DC8,9 PC) can self assemble into lipid nanotubules. This hollow cylindrical supramolecular structure shows promise in a number of biotechnological applications. The mechanism of lipid tubule formation was initiated by assembling of lipid bilayer sheets from amphiphilic
Jarinee, Kiang-ia +8 more
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Confocal Raman Microscopy of Protein Adsorbed in Chromatographic Particles
Analytical Chemistry, 2012Confocal Raman microscopy is a nondestructive analytical technique that combines the chemical information from vibrational spectroscopy with the spatial resolution of confocal microscopy. It was applied, for the first time, to measure conformation and distribution of protein adsorbed in wetted chromatographic particles.
Yuewu, Xiao +4 more
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Confocal Raman microscopy: common errors and artefacts
The Analyst, 2010Confocal Raman microscopy is a powerful tool for research and analysis in the chemical, materials and life sciences, particularly for non-destructive depth profiling of transparent systems. Unfortunately, many Raman microscopes are not optimally configured for this purpose, and so yield unnecessarily low signal-to-noise spectra with poor spatial ...
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Imaging of plant cell walls by confocal Raman microscopy
Nature Protocols, 2012Raman imaging of plant cell walls represents a nondestructive technique that can provide insights into chemical composition in context with structure at the micrometer level (
Gierlinger, Notburga, N. +2 more
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New Twists and Turns for Confocal Raman Microscopy
Frontiers in Optics, 2006Confocal Raman microscopes usually reject elastically scattered light. This light, however, carries information about the target’s angular scattering properties. Imaging this rejected beam creates a multimodal microscope with chemical (Raman) and structural (elastic scatter) capabilities.
Andrew J. Berger, Zachary J. Smith
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Characterization of Ionomer Membranes with Confocal Raman Microscopy
ECS Meeting Abstracts, 2020Ionomer membranes are crucial components of electrochemical energy systems such as fuel cells, electrolyzers, or redox-flow batteries. They need to meet demanding requirements for high-performance and long-term stable devices, and a targeted optimization of the membranes requires exact knowledge of parameters such as membrane thickness, ion exchange
Thomas Böhm +5 more
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Materials analysis using confocal Raman microscopy
Macromolecular Symposia, 1999AbstractThe recent development of Raman microscopes with high optical throughput and very sensitive CCD cameras has led to Raman spectroscopy again competing effectively with FTIR methods for materials analysis. Modern Raman instruments, designed to operate confocally without serious alignment or energy trade‐off problems, allow depth profiling of ...
Chris Sammon +4 more
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Confocal Raman Microscopy in Pharmaceutical Development
2010There is a wide range of applications of confocal Raman microscopy in pharmaceutical development. It is a powerful tool to probe the distribution of components within a formulation, to characterize homogeneity of pharmaceutical samples, to determine solid state of drug substances and excipients as well as to characterize contaminations and foreign ...
Thomas F. Haefele, Kurt Paulus
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Confocal fluorescence and Raman microscopy in industrial research
Colloid & Polymer Science, 1998Modern chemical and pharmaceutical industrial research benefits from improved spectroscopic tools. New developments in confocal fluorescence and Raman microscopy lead to an increase in sensitivity, selectivity and speed of microscopic imaging and fluctuation analysis resulting in a better understanding of structure–property relationships essential for ...
W. Schrof +3 more
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Three-Dimensional Digital Confocal Raman Microscopy
Applied Spectroscopy, 1993We describe an iterative image restoration technique which functions as digital confocal microscopy for Raman images. We deconvolute the lateral and axial components of the microscope point spread function from a series of optical sections, to generate a stack of well-resolved Raman images which describe the three-dimensional topology of a sample. The
Anurag Govil +2 more
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