Results 41 to 50 of about 1,748 (310)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A new conformable nabla derivative and its application on arbitrary time scales
Advances in Difference Equations, 2021 In this article, we introduce a new type of conformable derivative and integral which involve the time scale power function G ˆ η ( t , a ) $\widehat{\mathcal{G}}_{\eta }(t, a)$ for t , a ∈ T $t,a\in \mathbb{T}$ .
Mohamad Rafi Segi Rahmat +1 more
doaj +1 more source
Results in Physics, 2023 In this paper, the generalized (3+1)-dimensional nonlinear Sasa–Satsuma model with conformable fractional derivative using the new Kudryashov approach is considered to find a class of novel exact solutions in optical fibers.
Muhammad Amin S. Murad +4 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
Effective Approach to Construct Series Solutions for Uncertain Fractional Differential Equations
Fuzzy Information and Engineering, 2022 Purpose: We construct the analytical approximate resiual power fuzzy series solutions of fuzzy conformable fractional differential equations in an [Formula: see text]-level depiction in the sense of strongly generalized [Formula: see text]-fuzzy ...
Zeyad Al-Zhour +5 more
doaj +1 more source
Solving Higher-Order Fractional Differential Equations by the Fuzzy Generalized Conformable Derivatives [PDF]
, 2021 Atimad Harir +2 more
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye +11 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective The purpose was to evaluate a biomarker score consisting of MUC5B rs35705950 promoter variant, plasma matrix metalloproteinase‐7 (MMP‐7), and serum anti–malondialdehyde‐acetaldehyde (anti‐MAA) antibody for rheumatoid arthritis (RA)–associated interstitial lung disease (ILD) risk stratification.
Kelsey Coziahr +16 more
wiley +1 more source
International Journal of Differential Equations, 2021 In this paper, a novel analytical method for solving nonlinear partial differential equations is studied. This method is known as triple Laplace transform decomposition method. This method is generalized in the sense of conformable derivative.
Shailesh A. Bhanotar +1 more
doaj +1 more source