Results 51 to 60 of about 126,619 (278)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Analisys of Conformal Antennas for Avionics Applications [PDF]
Conformal antennas might have an important impact on communication and navigation applications on aircraft, ships and other vehicles. This thesis work presents a general study on conformal antennas and their potential application on aircraft structures ...
Redondo Gonzalez, Maria del Carmen
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
26 pages + References. Slight wording changes.
Luty, Markus A., Okui, Takemichi
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
This paper presents a three-medium, double-layer Frequency Selective Surface (FSS) structure that exhibits stable filtering characteristics, including stability with respect to incident angle and stability of filtering performance under misalignment ...
Yu Miao, Wang Jianbo, Xu Nianxi
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The Importance of Organ-Specific Setup Uncertainties Assessment for Determination of the Planning Target Volume Margin in Prostate and Cervical Cancer Using Electronic Portal Imaging Device (EPID) [PDF]
Introduction: The setup uncertainty is a significant issue in radiotherapy that affects the accuracy of the delivered dose to the clinical target volume (CTV).
Mohammad Yasin Mohammadi +7 more
doaj +1 more source
Genuine Dilatons in Gauge Theories
A genuine dilaton σ allows scales to exist even in the limit of exact conformal invariance. In gauge theories, these may occur at an infrared fixed point (IRFP) α IR through dimensional transmutation.
R. J. Crewther
doaj +1 more source

