Results 61 to 70 of about 126,619 (278)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Verification and correction of geometrical uncertainties in conformal radiotherapy [PDF]

Archive of Oncology, 2005
Geometrical errors are presented as deviation between intended geometry of radiotherapy plan and real geometry of radiotherapy treatment. Total geometrical error is build up of smaller errors, which can be generally classified as set-up, organ motion ...
Mileusnić Dušan
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Introduction to Quantization of Conformal Gravity

Universe, 2022
A method for consistent quantization of conformal gravity treating conformal symmetry in a very controllable way is presented. First, we discuss local conformal symmetry in the framework of gravitational interactions, where we view it as an example of a ...
Lesław Rachwał
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Stability and covergence properties of Bergman Kernel methods for numerical conformal mapping [PDF]

, 1984
In this paper we study the stability and convergence properties of Bergman kernel methods, for the numerical conform al mapping of simply and doubly- connected domains.
Warby, M K, Papamichael, N
core   +4 more sources

Design and Performance Measurement of Worn-on-Body Instrumental Ultra-Miniaturized UWB Wearable Patch for e-Health Monitoring

IEEE Access
A conformal, ultra-miniaturized, circuit integrated ultra-wideband (UWB) coplanar-waveguide (CPW) antenna system for worn-on-body applications is developed in this article.
Sumon Modak, Vikrant Kaim, Taimoor Khan, Binod Kumar Kanaujia, Ladislau Matekovits, Karumudi Rambabu   +5 more
doaj   +1 more source

Estudio y comparación en sistemas WTP basados en SCRM

Revista Vínculos, 2019
La transmisión inalámbrica de energía eléctrica es un tema que tiene una amplia aplicación en la ciencia, así que es necesario identificar cuál de sus diversos modelos se acoplan mejor de acuerdo con un requerimiento.
Pablo Emilio Rozo García, Nicolás Andrés Rozo Cruz, Carlos Andrés Cáceres Ramírez, Jhoyner Esteban Martínez Hernández   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source