Results 121 to 130 of about 115,904,991 (230)

Supervised Protein Structure Classification Using Topological Persistence With DeltaFold

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Recent advances in protein structure prediction have considerably increased the number of available structures, underscoring the need for scalable and accurate methods to compare and classify this huge amount of data. Current approaches based on sequence alignment or structural superposition often lack sensitivity and/or are computationally ...
Joseph Nardin‐Gennequin, Gabriela Ciuperca, Céline Brochier‐Armanet, Philippe Malbos   +3 more
wiley   +1 more source

Molecular Basis for Uracil‐DNA‐Glycosylase to Identify DNA Damage in the Nucleosome

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The DNA base‐excision repair (BER) pathway is initiated by a glycosylase, such as uracil‐DNA‐glycosylase (UDG), which identifies and removes a wrong base incorporated in the DNA sequence. The very early steps in the identification of the DNA damage are crucial to the correct initiation of the repair chain, and become even more complex when ...
Safwen Ghediri, Ralf Blossey, Fabrizio Cleri   +2 more
wiley   +1 more source

Betulinic Acid Enema Alleviates Colitis by Targeting Vitamin D Receptor to Protect the Intestinal Mucosal Barrier and Modulate Mucosa‐Associated Microbiota

Phytotherapy Research, EarlyView.
ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong, Yuanxia Gao, Qian Li, Guangxin Chen, Dong Yang, Liping Zhao, Xiaojing Liu, Shumei Lin   +7 more
wiley   +1 more source

Schisandrin C Targets PPARγ to Induce Ferroptosis in Colorectal Cancer Cells and Promote M1 Macrophage Polarization

Phytotherapy Research, EarlyView.
Schisandrin C: A Dual Anti‐Colorectal Cancer Strategy Targeting PPARγ. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer mortality, necessitating novel therapeutic strategies. Schisandrin C (SinC), a bioactive lignan from Schisandra chinensis, exhibits diverse pharmacological activities, but its anti‐CRC mechanisms are poorly ...
Xiao Wei, Hong‐Ping Wen, Jian‐Bo Song, Jin‐Fang Xu, Hong‐Rui Guo   +4 more
wiley   +1 more source

The CFT of Sen’s formulation of chiral gauge fields

Journal of High Energy Physics
Sen’s action for chiral bosons in 2 dimensions describes two chiral scalars, one of which couples to the physical metric and one of which couples to a flat metric. It has a generalisation in which the flat metric is replaced by an arbitrary second metric
Chris Hull, Neil Lambert
doaj   +1 more source

Science for All? A Systematic Literature Review on Effective Teaching Approaches in Inclusive and Separate Settings

Science Education, EarlyView.
ABSTRACT This systematic literature review examines intervention studies focused on teaching science to a diverse range of learners. It adopts a broad definition of inclusion and makes use of the PRISMA statement. The review aims to provide an overview of evidence‐based teaching approaches in the current literature, identify the science skills targeted,
Silvia Fränkel, Nadine Großmann, Melanie Basten   +2 more
wiley   +1 more source

Classifying three-character RCFTs with Wronskian index equalling 3 or 4

Journal of High Energy Physics
In the Mathur-Mukhi-Sen (MMS) classification scheme for rational conformal field theories (RCFTs), a RCFT is identified by a pair of non-negative integers [n, ℓ], with n being the number of characters and ℓ the Wronskian index.
Chethan N. Gowdigere, Sachin Kala, Jagannath Santara   +2 more
doaj   +1 more source

Corporate Social Responsibility and Corporate Misconduct: A Review of Empirical Research and Future Research Recommendations

Sustainable Development, EarlyView.
ABSTRACT This study reviews 54 empirical‐quantitative (archival) articles on the relationship between corporate social responsibility (CSR) outcomes and corporate misconduct. Based on the moral licensing and moral track hypotheses, we distinguish between CSR performance, reporting, and assurance on the one hand and between financial and CSR‐related ...
Patrick Velte
wiley   +1 more source

Solvable models of quantum black holes: a review on Jackiw-Teitelboim gravity. [PDF]

Living Rev Relativ, 2023
Mertens TG, Turiaci GJ.
europepmc   +1 more source

Toward a Sustainability Standard for Cultural Organizations: Borrowing From Tourism

Sustainable Development, EarlyView.
ABSTRACT Cultural organizations are increasingly engaging with sustainability, yet they lack a sector‐specific standard to guide and institutionalize efforts as long‐term strategies. This study reviews research papers on sustainability standards in the tourism sector, a field with greater experience with such tools, and horizontally borrows insights ...
Małgorzata Ćwikła, Leticia Labaronne
wiley   +1 more source