Results 81 to 90 of about 90,774 (312)

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

The Best Conic Conformal Map Projection for the Territory of Croatia

Kartografija i Geoinformacije, 2010
The paper gives an answer to the question: if the maritime area of Croatia (territorial sea and continental shelf) is involved, which is the best Lambert conic conformal map projection for the territory of Croatia?
Marina Rajakovic, Miljenko Lapaine
doaj  

Some results of the f-biharmonic maps and applications

Arab Journal of Mathematical Sciences, 2018
In this paper, we give some properties of the f-biharmonic maps, in the particular case represented by conformal maps between equidimensional manifolds.
Djelloul Djebbouri, Seddik Ouakkas
doaj   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Conformal interfaces between free boson orbifold theories

Journal of High Energy Physics, 2017
We construct a large class of conformal interfaces between two-dimensional c = 1 conformal field theories describing compact free bosons and their ℤ 2 $$ {\mathrm{\mathbb{Z}}}_2 $$ orbifolds. The interfaces are obtained by constructing boundary states in
Melanie Becker, Yaniel Cabrera, Daniel Robbins   +2 more
doaj   +1 more source

Conformal structure of FLRW cosmology: spinorial representation and the so $$ \mathfrak{so} $$ (2, 3) algebra of observables

Journal of High Energy Physics, 2020
It was recently shown that the homogeneous and isotropic cosmology of a massless scalar field coupled to general relativity exhibits a new hidden conformal invariance under Mobius transformation of the proper time, additionally to the invariance under ...
Jibril Ben Achour, Etera R. Livine
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Computing Quasiconformal Maps on Riemann surfaces using Discrete Curvature Flow

, 2010
Surface mapping plays an important role in geometric processing. They induce both area and angular distortions. If the angular distortion is bounded, the mapping is called a {\it quasi-conformal} map.
Chan, J. S. Liu T. F., Gu, X. F., Lui, L. M., Luo, F., Yau, S. T., Zeng, W.   +5 more
core  

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source