Results 81 to 90 of about 90,892 (317)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
On Makarov’s Principle in Conformal Mapping [PDF]
International Mathematics Research Notices, 2017 20 ...
openaire +6 more sources
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
The Best Conic Conformal Map Projection for the Territory of Croatia
Kartografija i Geoinformacije, 2010 The paper gives an answer to the question: if the maritime area of Croatia (territorial sea and continental shelf) is involved, which is the best Lambert conic conformal map projection for the territory of Croatia?
Marina Rajakovic, Miljenko Lapaine
doaj
Some results of the f-biharmonic maps and applications
Arab Journal of Mathematical Sciences, 2018 In this paper, we give some properties of the f-biharmonic maps, in the particular case represented by conformal maps between equidimensional manifolds.
Djelloul Djebbouri, Seddik Ouakkas
doaj +1 more source
Journal of High Energy Physics, 2020 It was recently shown that the homogeneous and isotropic cosmology of a massless scalar field coupled to general relativity exhibits a new hidden conformal invariance under Mobius transformation of the proper time, additionally to the invariance under ...
Jibril Ben Achour, Etera R. Livine
doaj +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Conformal interfaces between free boson orbifold theories
Journal of High Energy Physics, 2017 We construct a large class of conformal interfaces between two-dimensional c = 1 conformal field theories describing compact free bosons and their ℤ 2 $$ {\mathrm{\mathbb{Z}}}_2 $$ orbifolds. The interfaces are obtained by constructing boundary states in
Melanie Becker +2 more
doaj +1 more source
Computing Quasiconformal Maps on Riemann surfaces using Discrete Curvature Flow
, 2010 Surface mapping plays an important role in geometric processing. They induce both area and angular distortions. If the angular distortion is bounded, the mapping is called a {\it quasi-conformal} map.
Chan, J. S. Liu T. F. +5 more
core
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source