Results 111 to 120 of about 10,836 (311)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Conformal Mapping [PDF]

open access: yes, 1941
The purpose of this thesis is to give a simple interpretation of conformal mapping by some functions, showing how they map one plane upon the other, into what curves straight lines in one plane are carried over.
Mezynski, Ingonda Von
core  

Conductor loss calculation of elliptical, cylindrical coplanar waveguides and coplanar waveguides with finite conductor thickness [PDF]

open access: yes, 2009
In this paper, new and fast analytical formulations have been presented for conductor loss calculations of elliptical (ECPW) and cylindrical coplanar waveguide (CCPW) with finite conductor thickness.
Bayrak, Mehmet   +3 more
core   +1 more source

COMPLEX VARIABLE FUNCTION SOLUTIONS OF MIXED-MODE STRESS INTENSITY FACTORS FOR TWO CRACKS OF ARBITRARY LENGTH EMANATING FROM AN ELLIPTICAL HOLE

open access: yesJixie qiangdu, 2019
In order to calculate the stress intensity factors of two-dimensional cracks emanating from elliptical hole, a solution method for stress intensity factor based on Muskhelishvili complex function theory and truncated conformal mapping approach is ...
ZHU QingYu, ZHOU Rui
doaj  

The conformal gauge to the derivative gauge for worldsheet gravity

open access: yesPhysics Letters B, 2015
The BRST quantizations of worldsheet gravity corresponding to final more acceptable derivative gauge and the standard conformal gauge are studied. We establish a mapping between these two gauges utilizing FFBRST formulation in standard way. Therefore, we
Sudhaker Upadhyay
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

CONFORMAL MAPPING ANALYSIS OF VARIOUS COPLANAR WAVEGUIDE STRUCTURES [PDF]

open access: yesICTACT Journal on Communication Technology, 2012
A conformal mapping analysis of various coplanar waveguide structures is presented on silicon substrate. The analysis is based on quasi-TEM analysis which is used in formulating the electrical parameters of a transmission line.
B. Nataraj, K. Porkumaran
doaj  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

New method of calculating the wakefields of a point charge in a waveguide of arbitrary cross section

open access: yesPhysical Review Accelerators and Beams, 2016
A new method for calculating the Cherenkov wakefield acting on a point charged particle passing through a longitudinally homogeneous structure lined with layer(s) of an arbitrary retarding (dielectric, resistive, or corrugated) material has been ...
S. S. Baturin, A. D. Kanareykin
doaj   +1 more source

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