Results 91 to 100 of about 1,682,992 (297)
Optimization of Conformal Mapping Functions used in Developing Closed-Form Solutions for Underground Structures with Conventional cross Sections [PDF]
International Journal of Mining and Geo-Engineering, 2015 Elastic solutions applicable to single underground openings usually suffer from geometry related simplification. Most tunnel shapes possess two axes of symmetry while a wide range of geometries used in tunneling practice involve only one symmetry axis. D-
Ali Nazem +3 more
doaj
The approximate conformal mapping onto multiply connected domains
Проблемы анализа, 2019 The method of boundary curve reparametrization is generalized to the case of multiply connected domains. We construct the approximate analytical conformal mapping of the unit disk with N circular slits or an annulus with (N - 1) circular slits onto an ...
Abzalilov, Shirokova
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Fit-for-purpose conformal mapping for sustainable land administration in war-ravaged Syria. [PDF]
Heliyon, 2022 Habib M.
europepmc +1 more source
, 2014 The conformal mapping formulation for the free-surface Euler equations in the presence of non homogeneous, yet stationary bathymetry is here derived and numerically implemented.
C. Viotti, D. Dutykh, F. Dias
semanticscholar +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
AIP AdvancesIn this study, we investigate the influence of pinning forces and conformal mapping parameters on the critical current density of superconductor tapes. By applying dual conformal transformations to triangular pinning arrays, we utilize molecular dynamics
Z. Owjifard, A. Tavana, M. Hosseini
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source