Results 71 to 80 of about 1,682,992 (297)
Journal of High Energy Physics, 2019 We show that the simplest FLRW cosmological system consisting in the homo- geneous and isotropic massless Einstein-Scalar system enjoys a hidden conformal symmetry under the 1D conformal group SL(2, ℝ) acting as Mobius transformations in proper time ...
Jibril Ben Achour, Etera R. Livine
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
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Conformal Mappings of Mixed Generalized Quasi-Einstein Manifolds Admitting Special Vector Fields
Extracta Mathematicae, 2017 It is known that Einstein manifolds form a natural subclass of the class of quasi-Einstein manifolds and plays an important role in geometry as well as in general theory of relativity.
S. Dey, A. Bhattacharyya
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Inhomogeneous dielectrics: conformal mapping and finite-element models
Open Physics, 2017 Field singularities in electrostatic and magnetostatic fields require special attention in field calculations, and today finite element methods are normally used, both in homogeneous and in inhomogeneous dielectric cases.
Costamagna Eugenio, Barba Paolo Di
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
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PROSPECTS OF WIDER USE OF THE OF COMPLEMENTARITY AND CONGRUENCE CONCEPT IN PRACTICAL MEDICINE
Medična Informatika ta Inženerìâ, 2015 It was discussed the possibility of widespread use of the complementarity and congruence concepts in medicine. It is proposed to use a simple functional to formalize therapeutic strategy is a reflection of the diagnostic and follow-conformal mapping ...
O. P. Mintser, L. Yu. Babintseva
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
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