Advanced Science, EarlyView.This study demonstrates multimodal integration in non‐human primates, combining large‐scale, high‐density electrophysiology using Smart Dura with optical techniques such as multiphoton imaging (MPI), photothrombotic lesioning, optical coherence tomography angiography (OCTA), wide‐field intrinsic signal optical imaging (ISOI), and optogenetics.
Nari Hong +10 more
wiley +1 more source
Robotic conformal 4D printing of liquid crystal elastomers. [PDF]
Sci AdvChung C +4 more
europepmc +1 more source
Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells
Advanced Science, EarlyView.Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale +6 more
wiley +1 more source
Highest-Weight Vectors and Three-Point Functions in GKO Coset Decomposition. [PDF]
Commun Math PhysBershtein M, Feigin B, Trufanov A.
europepmc +1 more source
Conformal Vector Fields in Compact Riemannian Manifolds [PDF]
Proceedings of the American Mathematical Society, 1963 openaire +2 more sources
Recent Advances in Decoupling Strategies for Soft Sensors
Advanced Science, EarlyView.This review provides an overview of recent advances in decoupling strategies for soft sensors. It summarizes single‐modal sensors that are insensitive to stretching, bending, crosstalk, and other environmental interferences, and highlights emerging multimodal decoupling methods enabled by spatiotemporal information and machine learning.
Yangbo Yuan +4 more
wiley +1 more source
Reassessing the foundations of metric-affine gravity. [PDF]
Eur Phys J C Part FieldsFrançois J, Ravera L.
europepmc +1 more source
Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease
Advanced Science, EarlyView.ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan +17 more
wiley +1 more source
Cross-Modal Interaction Fusion-Based Uncertainty-Aware Prediction Method for Industrial Froth Flotation Concentrate Grade by Using a Hybrid SKNet-ViT Framework. [PDF]
Sensors (Basel)Lu F, Gui W, Wang Y, Zhou J, Wang X.
europepmc +1 more source
Discovery of SKP2‐Recruiting PROTACs for Target Protein Degradation
Advanced Science, EarlyView.Based on the SKP2‐targeting ligand SL1, we designed non‐covalent PROTACs by linking it with the BRD4 inhibitor JQ1 and the AR antagonist AL through a linker. These PROTACs successfully induced the ubiquitination of BRD4 and AR, followed by proteasome‐mediated degradation.
Guanjun Dong +13 more
wiley +1 more source