Results 121 to 130 of about 206,324 (261)
Acta Crystallographica Section E: Crystallographic Communications, 2015 The title compound, C22H20N4O3S, features two fused six-membered rings linked to a 1,2,3-triazole ring which is attached to an ethyl acetate group. The heterocycle in the benzothiazine residue has an envelope conformation with the S atom being the flap ...
M. Ellouz +4 more
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
, 2018 Hierarchical self-assembly of synthetic polypeptides has attracted increasing interests due to its protein-mimetic structure and great potential in nanotechnology and biomedical applications.
Yi Zheng (113896) +9 more
core +1 more source
Beilstein Journal of Organic Chemistry, 2017 Fluorinated moieties are highly valuable to chemists due to the sensitive NMR detectability of the 19F nucleus. Fluorination of molecular scaffolds can also selectively influence a molecule’s polarity, conformational preferences and chemical reactivity ...
Vladimir Kubyshkin, Nediljko Budisa
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
RESEARCH CONCERNING MORPHO CHARACTERISTICS OF ROMANIAN BLACK SPOTTED BREEDED IN CONDITION OF S.C. BIOTERA FARM, ALBA COUNTY [PDF]
Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2013 Researches regarding morpho characteristics of Romanian Black Spotted breed were performed on 56 cows bull daughters in testing and candidate as bull's mother, raised and exploited in SC Biotera SRL farm from Alba county and has as database, records of ...
Alin AVRAM +2 more
doaj
Silyl-protective groups influencing the reactivity and selectivity in glycosylations
Beilstein Journal of Organic Chemistry, 2017 Silyl groups such as TBDPS, TBDMS, TIPS or TMS are well-known and widely used alcohol protective groups in organic chemistry. Cyclic silylene protective groups are also becoming increasingly popular. In carbohydrate chemistry silyl protective groups have
Mikael Bols, Christian Marcus Pedersen
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Conformation generation method.
, 2013 Conformation generation method.
Jérôme Azé (120415) +3 more
core +1 more source
Beilstein Journal of Organic Chemistry, 2014 Structural studies of pentapeptides containing an achiral block, built from two dehydroamino acid residues (ΔZPhe and ΔAla) and two glycines, as well as one chiral L-Val residue were performed using NMR spectroscopy.
Michał Jewgiński +4 more
doaj +1 more source