Results 131 to 140 of about 206,324 (261)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Isoleucine gate blocks K+ conduction in C-type inactivation

eLife
Many voltage-gated potassium (Kv) channels display a time-dependent phenomenon called C-type inactivation, whereby prolonged activation by voltage leads to the inhibition of ionic conduction, a process that involves a conformational change at the ...
Werner Treptow, Yichen Liu, Carlos AZ Bassetto, Bernardo I Pinto, Joao Antonio Alves Nunes, Ramon Mendoza Uriarte, Christophe J Chipot, Francisco Bezanilla, Benoit Roux   +8 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Quantification of the structural preference of the α-helical V2^167-179 conformation for the β-sheet conformation.

, 2017
Quantification of the structural preference of the α-helical V2167-179 conformation for the β-sheet conformation.
Michael Goger (3687400), Phillip W. Berman (158435), Shibani Battacharya (3687394), Evgeny Shmelkov (340162), Peter B. Gilbert (30581), Timothy Cardozo (193921), Allan C. deCamp (3687397), Mohammed S. Aiyegbo (411505), Lorenzo Dominguez (3687391)   +8 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Conformation-Dependent Monolayer and Bilayer Structures of an Alkylated TTF Derivative Revealed using STM and Molecular Modeling

In this study, the multilayer self-assembled molecular network formation of an alkylated tetrathiafulvalene compound is studied at the liquid–solid interface between 1-phenyloctane and graphite.
Andrea Minoia (1894192), Kunal S. Mali (1455109), Catarina L. Delfino (17395050), Sandra Van Aert (7547783), Yansong Hao (1396180), Cristina Martin (1698814), Elumalai Gopi (1763356), Mark Van der Auweraer (1475641), Yves Henri Geerts (1864393), Steven De Feyter (7345211), Roberto Lazzaroni (1449016)   +10 more
core   +1 more source

Snapshots of the unbiased simulation of T:G. a) Two-hydrogen bonds conformation, b) one-hydrogen bond conformation.

, 2013
Snapshots of the unbiased simulation of T:G. a) Two-hydrogen bonds conformation, b) one-hydrogen bond conformation.
Petra Imhof (103245), Mai Zahran (103251)   +1 more
core   +1 more source

Conformation of cyclealkans [PDF]

, 2018
Молекули циклоалканів можуть перебувати в різних просторових формах (конформаціях). Розглянуто типи напруження в циклічних молекулах, різноманітні конформації циклоалканів залежно від розміру циклу.The molecule of cyclealkans may be in different spatial ...
Ковтуненко, В.О., Величко, Л. П.   +1 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Interatomic distances observed in the apo structure, the holo structure, the oxidized average conformation and the reduced average conformation.

, 2018
Interatomic distances observed in the apo structure, the holo structure, the oxidized average conformation and the reduced average conformation.
Amanda Souza Câmara (4876003), Eduardo Horjales (4838802)   +1 more
core   +1 more source