Results 201 to 210 of about 1,518,966 (331)

Modulatory Effect of Natural Antioxidants on Tissue Transglutaminase Levels in Olfactory Ensheathing Cells Exposed to Amyloid-β: Integrated Biochemical and Computational Analysis. [PDF]

Biofactors
Pellitteri R, Tomasella C, Chiacchio MA, Pappalardo M, Legnani L, Spatuzza M, Massaro A, Guccione S, Campisi A.   +8 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Conformation-selective detection of residues in solid proteins under magic-angle-spinning. [PDF]

J Biomol NMR
Parida PP, Taware PP, Mote KR.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Biomimetic actuator crafted from a relaxor ferroelectric polymer nanocomposite. [PDF]

Nat Commun
Chi H, Bai P, Zhou Z, Wang G, Xu W, Zhang Y, Qin H, Wang X, Zhang Y, Ma R.   +9 more
europepmc   +1 more source

Hi-C: a comprehensive technique to capture the conformation of genomes.

Methods, 2012
Jon-Matthew Belton, R. McCord, J. Gibcus, N. Naumova, Y. Zhan, J. Dekker   +5 more
semanticscholar   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Guiding AlphaFold predictions with experimental knowledge to inform dynamics and interactions with VAIRO. [PDF]

Protein Sci
Triviño J, Jiménez E, Grininger C, Caballero I, Medina A, Castellví A, Petrillo G, Govantes F, Sagmeister T, Alcorlo M, Hermoso JA, Sammito MD, Diederichs K, Pavkov-Keller T, Usón I.   +14 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Crystal structure of Methanococcus jannaschii dihydroorotase with substrate bound. [PDF]

Acta Crystallogr F Struct Biol Commun
Vitali J, Nix JC, Newman HE, Colaneri MJ.   +3 more
europepmc   +1 more source