Results 261 to 270 of about 497,883 (326)

Geniposidic Acid Targeting FXR "S332 and H447" Mediated Conformational Change to Upregulate CYPs and miR-19a-3p to Ameliorate Drug-Induced Liver Injury. [PDF]

Adv Sci (Weinh)
Fan M, Xu Y, Wu B, Long J, Liu C, Liang Z, Zhang R, Liu Z, Wang C.   +8 more
europepmc   +1 more source

SI‐bioATRP in Mesoporous Silica for Size‐Exclusion Driven Local Polymer Placement

Advanced Functional Materials, EarlyView.
An enzyme‐catalyzed surface‐initiated atom transfer radical polymerization (SI‐bioATRP) of an anionic monomer within mesoporous silica particles, using hemoglobin as a catalyst, allows for controlling the location of the formed polymer via size‐exclusion effects between the nanopores and the biomacromolecules, thereby opening routes to functional ...
Oleksandr Wondra, Eleonora Ornati, Robert Lehn, Joanna J. Mikolei, Hergen Breitzke, Raheleh Pardehkhorram, Gerd Buntkowsky, Nico Bruns, Annette Andrieu‐Brunsen   +8 more
wiley   +1 more source

Evidence for a model of conformational change by the <i>Plasmodium falciparum</i> circumsporozoite protein during sporozoite development in the mosquito host through the use of camelid single-domain antibodies. [PDF]

Infect Immun
Geens R, De Vocht L, Aguirre-Botero MC, Vincke C, Romão E, Magez S, Muyldermans S, Amino R, Sterckx YG-J.   +8 more
europepmc   +1 more source

Liquid Crystalline Inverted Lipid Phases and Reverse Micelles in Drug Delivery: From Molecular Design to Therapeutic Potential

Advanced Functional Materials, EarlyView.
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu, Mulazim Hussain Asim, Soheil Haddadzadegan, Andreas Bernkop‐Schnürch   +3 more
wiley   +1 more source

Molecular structure and selective theophylline complexation by conformational change of diethyl N,N'-(1,3-phenylene)dicarbamate. [PDF]

Acta Crystallogr C Struct Chem
González-González JS, Martínez-Santos A, Emparán-Legaspi MJ, Pineda-Contreras A, Martínez-Martínez FJ, Flores-Alamo M, García-Ortega H.   +6 more
europepmc   +1 more source

Role of Histidine‐Containing Peptoids in Accelerating the Kinetics of Calcite Growth

Advanced Functional Materials, EarlyView.
Amphiphilic histidine‐containing peptoids mimic carbonic anhydrase (CA) to accelerate calcite step growth. In the presence of Zn2+, they promote the deprotonation of HCO3−, the desolvation of Ca2+, and the reorganization of interfacial hydration layers, thereby reducing the activation barrier for calcite growth.
Mingyi Zhang, Ying Chen, Chenyang Shi, Progyateg Chakma, James J. De Yoreo, Chun‐Long Chen   +5 more
wiley   +1 more source

β-sheets mediate the conformational change and allosteric signal transmission between the AsLOV2 termini. [PDF]

J Comput Chem
Xiao S, Ibrahim MT, Verkhivker GM, Zoltowski BD, Tao P.   +4 more
europepmc   +1 more source

High‐Resolution Characterization of Protein‐Conjugated, mRNA‐Loaded Lipid Nanoparticles by Analytical Ultracentrifugation

Advanced Functional Materials, EarlyView.
Lipid nanoparticles containing messenger RNA are characterized by sedimentation velocity analytical ultracentrifugation using UltraScan's new Custom Grid algorithm to provide multi‐dimensional distributions for partial specific volume (particle density), molar mass, sedimentation, diffusion, and hydrodynamic radius.
Sophia Bird, Connor Smith, Nahal Habibi, Samantha Rivera, Saeed Mortezazadeh, Reece Martin, Benjamin M. Geilich, Gilles Besin, Borries Demeler   +8 more
wiley   +1 more source

A Total Internal Reflection Microscopy (TIRM)-Based Approach for Direct Characterization of Polymer Brush Conformational Change in Aqueous Solution. [PDF]

ACS Macro Lett
Wu J, Cao F, Yeung PWF, Li M, Ohno K, Ngai T.   +5 more
europepmc   +1 more source