Results 301 to 310 of about 497,883 (326)

Conformational changes in corticotropin solutions

Biochimica et Biophysica Acta (BBA) - Specialized Section on Biophysical Subjects, 1964
Abstract The behaviour and physico-chemical characteristics of corticotropin, or adrenocorticotropic hormome (ACTH), in aqeous solution as a function of ionic strength and temperature have been studied. It is shown that sharp changes of physico-chemical properties of the solution take place when both temperature or ionic strength reach critical ...
C, BOTRE, M, SOLINAS
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Conformational Changes in Protein Function

2008
Conformational changes are the hallmarks of protein dynamics and are often intimately related to protein functions. Molecular dynamics (MD) simulation is a powerful tool to study the time-resolved properties of protein structure in atomic details.
Haiguang, Liu, Shubhra Ghosh, Dastidar, Hongxing, Lei, Wei, Zhang, Matthew C, Lee, Yong, Duan   +5 more
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Conformational changes in histone IV

Biopolymers, 1972
AbstractConformational change of histone IV, induced by phosphate, have been investigated by observing the intrinsic fluorescence of tyrosine residues and circular dichroism (CD). There is a fast conformational change upon the addition of phosphate, followed by a slow process with time constants in the range of minutes to hours depending upon both the ...
H J, Li, R, Wickett, A M, Craig, I, Isenberg   +3 more
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Isotopomeric Conformational Change in Anisole–Water

Angewandte Chemie, 2005
The deuteration of water produces a conformational change in the Anisole×××Water complex, as shown by the scheme. The value of the q angle decreases from 138 to 128°, while the secondary interaction O×××HMe is replaced by the O×××HPh one.
GIULIANO, BARBARA MICHELA, CAMINATI, WALTHER   +1 more
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Allostery without conformational change

European Biophysics Journal, 1984
A general model is presented whereby ligand-induced changes in protein dynamics could produce allosteric communication between distinct binding sites, even in the absence of a macromolecular conformational change. Theoretical analysis, based on the statistical thermodynamics of ligand binding, shows that cooperative interaction free energies amounting ...
A, Cooper, D T, Dryden
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Conformational changes in biological macromolecules

Biorheology, 1984
Some known conformational changes occurring in proteins and peptides are summarized and discussed. A novel nonradiative energy transfer technique, enabling evaluation of the conformation and intramolecular motility of polypeptides in solution, is described.
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Premelting Changes in DNA Conformation

1976
Publisher Summary This chapter discusses that Deoxyribonucleic acid (DNA) premelting has been demonstrated under conditions preceding thermal, acidic, and alkaline denaturation of aqueous DNA solutions. Certain signs of premelting changes have been discussed to arise from the addition of organic solvent to DNA solution.
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Conformational Changes of Acetylcholinesterase

Molecular Pharmacology, 1968
R J, Kitz, L T, Kremzner
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Conformation changes or cooperativity?

Science, 2018
Neurodegeneration Parkin is a commonly mutated protein ubiquitin ligase implicated in Parkinson's disease. Understanding how Parkin functions is important to understanding its pathogenic role. In a Perspective, Arkinson and Walden discuss recent structural insights into the activities of Parkin.
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pH-dependent conformational change of gastrin

Nature, 1974
GASTRIN is a polypeptide hormone with a broad spectrum of biological activities, most notably the stimulation of secretion of gastric acid1,2. It is produced primarily in the pyloric gland area of the lower segment of the stomach, the antrum, which does not secrete acid1,2.
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