Results 71 to 80 of about 14,468,474 (325)
Structure of FcRY, an avian immunoglobulin receptor related to mammalian mannose receptors, and its complex with IgY [PDF]
, 2011 Fc receptors transport maternal antibodies across epithelial cell barriers to passively immunize newborns. FcRY, the functional counterpart of mammalian FcRn (a major histocompatibility complex homolog), transfers IgY across the avian yolk sac, and ...
BENNETT +22 more
core +3 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Calmodulin: The switch button of calcium signaling
Tzu Chi Medical Journal, 2022 Calmodulin (CaM), a calcium sensor, decodes the critical calcium-dependent signals and converts them into the driving force to control various important cellular functions, such as ion transport.
Chiu-Fen Yang, Wen-Chin Tsai
doaj +1 more source
DNA unwinding heterogeneity by RecBCD results from static molecules able to equilibrate. [PDF]
, 2013 Single-molecule studies can overcome the complications of asynchrony and ensemble-averaging in bulk-phase measurements, provide mechanistic insights into molecular activities, and reveal interesting variations between individual molecules.
Baskin, Ronald J +2 more
core
Electron Transfer Precedes ATP Hydrolysis during Nitrogenase Catalysis [PDF]
, 2013 The biological reduction of N2 to NH3 catalyzed by Mo-dependent nitrogenase requires at least eight rounds of a complex cycle of events associated with ATP-driven electron transfer (ET) from the Fe protein to the catalytic MoFe protein, with each ET ...
Antony, Edwin +7 more
core +2 more sources
FEBS Letters, EarlyView.Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source
Ligand Binding, Protein Fluctuations, and Allosteric Free Energy [PDF]
, 2006 Although the importance of protein dynamics in protein function is generally recognized, the role of protein fluctuations in allosteric effects scarcely has been considered.
Wall, Michael E.
core +2 more sources
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Mining electron density for functionally relevant protein polysterism in crystal structures. [PDF]
, 2010 This review focuses on conceptual and methodological advances in our understanding and characterization of the conformational heterogeneity of proteins.
Fraser, James S, Jackson, Colin J
core +3 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source