Results 101 to 110 of about 755,354 (398)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

The Investigation of Porcelain Plates Roughness Influence on Determination of Explosives Friction Sensitivity

open access: yesApplied Sciences
The influence of the roughness of porcelain plates on the results of the friction sensitivity test of explosives was investigated. For this purpose, the roughness of selected batches of plates from several manufacturers (Julius Peters, OZM Research s.r.o.
Sonia Nachlik, Mateusz Pytlik
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Risks for the readymix concrete producer and contractor according to the acceptance or rejection criteria specified in different standards (part II)

open access: yesMateriales de Construccion, 2006
This paper continues the work done on Part I included in this Volume. Based on the conformity and acceptance criteria analysed on Part I (1), EN 206-1:2000 (2) and AC/-318 (3) standards are studied and compared to EHE (4) standard described in Part l ...
D. M. Prada Betancourt   +3 more
doaj   +1 more source

Essentially Derived Varieties in Ornamentals [PDF]

open access: yes, 2009
The concept of Essentially derived varieties (EDVs) was introduced in the UPOV 1991 act to protect the interests of the breeder of the initial variety. When a variety is considered as an EDV, authorisation for commercial exploitation is needed from the ...
Vosman, B.
core   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Conformity of finished forming sieves for paper industry

open access: yesProduction Engineering Archives, 2019
The sieves’ manufacturers that want to be competitive at the market must have the implemented quality control system. Different methods, based on taking the sample, which is a representative of the total quantity of the forming sieves production, are ...
Nada Bojić   +2 more
doaj   +1 more source

Another way of thinking: creativity and conformity [PDF]

open access: yes, 2007
This paper explores possible tactics for academics working within a context of regulation and constraint. One tactic we suggest is moving outside of a creativity/conformity binary.
Bohemia, Erik, Harman, Kerry
core   +1 more source

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