Results 111 to 120 of about 170,814 (256)
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Cohesiveness-Conformity Relationship and Conformity Instrumentality
, 1972 A perceptual judgmental situation with a Crutchfield-type apparatus was used with 128 Ss to test the hypothesis that a relationship between conformity and cohesiveness appears only when conformity is seen as being instrumental to attaining a group goal.
Robert L. Jovick
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Conformity Within the Campbell Paradigm: Proposing a New Measurement Instrument
, 2019 Conformity – people’s propensity to comply with the norms and expectations of others – is an important driver of behavior. In this research, we develop a measure of people’s level of conformity which is grounded in an innovative paradigm from attitude ...
Kaiser, Florian G. +3 more
core +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Role of Conformity Assessment in Global Market
The effects of globalization are increasingly felt all over the world. The world is becoming more homogeneous, since different kinds of products can be offered to a wider range of customers.
Mazais, Jānis +2 more
core
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
The wedding paradox: individualised conformity
, 2015 Marriage rates are historically low, almost half of marriages end in divorce, and it has never been easier to live in other relationship forms like cohabitation and LAT (living apart together).
Carter, J.
core
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source