Results 111 to 120 of about 139,209 (314)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Impact of nitromethane additive on ANFO performance

open access: yesScientific Reports
The article presents an evaluation of the detonation performance of a nitromethane-ammonium nitrate fuel oil energetic material. The brisance and relative strength of this material were assessed using the Hess and Trauzl methods.
Andrzej Biessikirski   +3 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Dynamic Models of Religious Conformity and Conversion: Theory and Calibrations [PDF]

open access: yes
This paper develops behavioral and deterministic overlapping generations models to explain and simulate changes in the proportion of secular and religious people.
Oz Shy
core  

Cohesiveness-Conformity Relationship and Conformity Instrumentality

open access: yes, 1972
A perceptual judgmental situation with a Crutchfield-type apparatus was used with 128 Ss to test the hypothesis that a relationship between conformity and cohesiveness appears only when conformity is seen as being instrumental to attaining a group goal.
Robert L. Jovick
core   +1 more source

Social Cognition 2.0: Toward Mechanistic Theorizing

open access: yesFrontiers in Psychology, 2019
Social cognition emerged in the 1970s and 80s as an attempt to answer social-psychological questions by adopting experimental techniques and theoretical concepts from cognitive psychology.
Diana Kim   +3 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Conformity Within the Campbell Paradigm: Proposing a New Measurement Instrument

open access: yes, 2019
Conformity – people’s propensity to comply with the norms and expectations of others – is an important driver of behavior. In this research, we develop a measure of people’s level of conformity which is grounded in an innovative paradigm from attitude ...
Kaiser, Florian G.   +3 more
core   +1 more source

Faith, Youth Brigade, No Labels, Corrosion of Conformity and Committee for Public Safety concert flier, Space II Arcade, Washington, D.C., August 17, 1983

open access: yes, 1983
Flier advertising The Faith's farewell concert featuring No Labels, Corrosion of Conformity, Scam, and Committee for Public Safety performing at Space II Arcade in Washington, D.C.

core   +1 more source

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