Results 101 to 110 of about 170,814 (256)
A Behavioral Model of Conumption Patterns: The Effects of Cognitive Dissonance and Conformity [PDF]
Cognitive dissonance causes people to rationalize actions that differ from their own preferences.Conformity, on the other hand, causes people to change their behavior as a result of pressure from others.This paper investigates the consequences of ...
Nir, A.
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The Effectiveness of Physical Practices on the Reduction of Slow-Pace Students’ Aggression [PDF]
The aim of this study was to determine the effectiveness of physical practices on the reduction of slow-pace children's aggression. For this purpose, 20 guidance school students with slow pace were selected through simple random sampling.
Gholamali Afrouz +3 more
doaj
BETWEEN THE RIGHT AND THE COMMON. HOW GROUPS REACT TO SOCIALLY UNDESIRABLE BEHAVIOUR
The aim of the paper is to analyse the relationship between group characteristics and the scope of reaction of the group to socially undesirable behaviour.
Komendant-Brodowska Agata
doaj +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Flier advertising The Faith's farewell concert featuring No Labels, Corrosion of Conformity, Scam, and Committee for Public Safety performing at Space II Arcade in Washington, D.C.
core
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Trends of Measuring Instruments Conformity Assessment
The aim of the paper is to show main points of measuring instruments conformity assessment to which need to pay attention and which can be changed in nearest future.
Liepiņa, Raimonda
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