Results 101 to 110 of about 170,814 (256)

A Behavioral Model of Conumption Patterns: The Effects of Cognitive Dissonance and Conformity [PDF]

open access: yes
Cognitive dissonance causes people to rationalize actions that differ from their own preferences.Conformity, on the other hand, causes people to change their behavior as a result of pressure from others.This paper investigates the consequences of ...
Nir, A.
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

The Effectiveness of Physical Practices on the Reduction of Slow-Pace Students’ Aggression [PDF]

open access: yesرشد و یادگیری حرکتی ورزشی, 2009
The aim of this study was to determine the effectiveness of physical practices on the reduction of slow-pace children's aggression. For this purpose, 20 guidance school students with slow pace were selected through simple random sampling.
Gholamali Afrouz   +3 more
doaj  

BETWEEN THE RIGHT AND THE COMMON. HOW GROUPS REACT TO SOCIALLY UNDESIRABLE BEHAVIOUR

open access: yesStudies in Logic, Grammar and Rhetoric, 2017
The aim of the paper is to analyse the relationship between group characteristics and the scope of reaction of the group to socially undesirable behaviour.
Komendant-Brodowska Agata
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Faith, No Labels, Corrosion of Conformity, Scam, and Committee for Public Safety concert flier, Space II Arcade, Washington, D.C., August 17, 1983

open access: yes, 1983
Flier advertising The Faith's farewell concert featuring No Labels, Corrosion of Conformity, Scam, and Committee for Public Safety performing at Space II Arcade in Washington, D.C.

core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Trends of Measuring Instruments Conformity Assessment

open access: yes
The aim of the paper is to show main points of measuring instruments conformity assessment to which need to pay attention and which can be changed in nearest future.
Liepiņa, Raimonda
core  

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