Results 101 to 110 of about 139,209 (314)
The conformity of goods, digital content and digital services with the contract in EU law
, 2022 Directive 2019/771/EU, which repealed Directive 1999/44/EC, and Directive 2019/770/EU, completely rewrote and extended the rules on conformity guarantees that professional sellers are required to offer to consumer purchasers for lack of conformity, with ...
Marina Pianoforte
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Conformity and Diversity in Budgetary Systems
, 2021 In modern democratic regimes the authorization and use of public resources involves forms of representation, consultation, degrees of transparency and accountability; in authoritarian or absolutist regimes these attributes will be less apparent although ...
John Wanna, Wanna, J
core +1 more source
Social Influence, 2017 Over the last decade, social media has increasingly been used as a platform for political and moral discourse. We investigate whether conformity, specifically concerning moral attitudes, occurs in these virtual environments apart from face-to-face ...
Meagan Kelly +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
On the Emergence of Social Norms [PDF]
, 2007 We consider a model of conformity that permits a non-conformist equilibrium and multiple conformist equilibria. Agents are assumed to behave according to a best reply learning dynamic.
Cartwright, Edward
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Conformorality. A Study on Group Conditioning of Normative Judgment. [PDF]
, 2012 How does other people’s opinion affect judgments of norm transgressions? In our study, we used a modification of the famous Asch paradigm (1951, 1955) to examine conformity in the moral domain.
Nilsenova, Marie +2 more
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source