Results 121 to 130 of about 139,209 (314)

The Sincerity of Questioned People

open access: yesEuropean Review Of Applied Sociology, 2016
Applying questionnaires is one of the basic methodologies in sociology. Usually sociologists consider that choosing a representative sample and properly formulated questions, the results will show real characteristics of the society.
Haller István
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Justificative conformity in ontologically ring-fenced fields: Problematizing the scholarly nomenclature in qualitative studies [PDF]

open access: yes
Ontology is implicitly or explicitly the impetus of any study. However, what are the implications of a scholarly field whose prevailing ontological assumptions and resultant epistemological commitments impede more nuanced theorizing?
Poulis, K., Christodoulou, I.
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Contributions to Conformable and non-Conformable Calculus

open access: yes, 2019
In this work, we introduce a definition of a local fractional derivative and a fractional integral of order alfa > 0 (where this parameter does not need to be integer), with which we overcome some deficiencies of known local derivatives, conformable or not. This definition allows to compute fractional derivatives of functions defined on any open set on
openaire   +3 more sources

The Effectiveness of Physical Practices on the Reduction of Slow-Pace Students’ Aggression [PDF]

open access: yesرشد و یادگیری حرکتی ورزشی, 2009
The aim of this study was to determine the effectiveness of physical practices on the reduction of slow-pace children's aggression. For this purpose, 20 guidance school students with slow pace were selected through simple random sampling.
Gholamali Afrouz   +3 more
doaj  

BETWEEN THE RIGHT AND THE COMMON. HOW GROUPS REACT TO SOCIALLY UNDESIRABLE BEHAVIOUR

open access: yesStudies in Logic, Grammar and Rhetoric, 2017
The aim of the paper is to analyse the relationship between group characteristics and the scope of reaction of the group to socially undesirable behaviour.
Komendant-Brodowska Agata
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Social conformity and equilibrium in pure strategies in games with many players [PDF]

open access: yes, 2002
We introduce a framework of noncooperative pregames, in which players are characterized by their attributes, and demonstrate that for all games with sufficiently many players, there exist approximate (e )Nash equilibria in pure strategies.
Wooders, Myrna Holtz   +2 more
core  

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