Results 121 to 130 of about 1,031,416 (263)
The terms independent variables, covariates, confounding variables , and confounding by indication are often imprecisely used in the context of regression.
Chittaranjan Andrade
core +1 more source
Confounding as a Result of Differential Diagnosis
, 1982 Confounding occurs when a competing cause of illness is associated with one or more of the factors being examined under the study hypothesis. Factors that influence the likelihood of diagnosis and are associated with exposure will also have confounding ...
Jørn Olsen
core +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
An theoretical and empirical evaluation of confounding mechanisms in the analysis of the health effects associated with long-term exposure to air pollution, with a case-study example using the UK Biobank cohort.
Vanoli, Jacopo, Gasparrini, Antonio
core +1 more source
Simpson's Paradox Beyond Confounding [PDF]
Simpson's paradox (SP) is a statistical phenomenon where the association between two variables reverses, disappears, or emerges, after conditioning on a third variable.
Cai, Weixin, Dong, Zili, Zhao, Shimin
core
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Adjusting for spatial confounding using eigendecomposed CAR models
, 2022 Observational epidemiological studies analyzed via spatial regression methods are often affected by spatial confounding. We formulate an adjustment strategy based on spectral methods, by considering eigendecomposed conditional autoregressive models.
Ventrucci, Massimo, Page, Garritt L
core
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source