Results 101 to 110 of about 762,252 (305)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Vaccine hesitancy was not shown to be associated with traffic safety or driver behavior

Frontiers in Public Health, 2023
Jeff Wilson, Claus Rinner, Anna Pefoyo Kone, Edward Bosveld   +3 more
doaj   +1 more source

Multiple Linear Regression Analysis Adjusted by Confounding Factors.

, 2014
...
Takashi Kudo (399517), Naomi Hayashida (297119), Ai Haraguchi (655459), Takao Ando (655463), Izumi Miyamoto (655461), Hironori Yamasaki (655465), Toshihiko Kamasaki (655460), Kenya Chiba (655466), Atsushi Kawakami (398370), Norio Abiru (655464), Noboru Takamura (297135), Toshiya Usui (655462)   +11 more
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Conditioning-induced cardioprotection: Aging as a confounding factor

The Korean Journal of Physiology & Pharmacology, 2018
The aging process induces a plethora of changes in the body including alterations in hormonal regulation and metabolism in various organs including the heart. Aging is associated with marked increase in the vulnerability of the heart to ischemia-reperfusion injury.
Randhawa, Puneet Kaur, Bali, Anjana, Virdi, Jasleen Kaur, Jaggi, Amteshwar Singh   +3 more
openaire   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Possible confounding factors on cerebral diffusion tensor imaging measurements

Acta Radiologica Open, 2015
Background Diffusion tensor imaging (DTI) is prone to numerous systemic confounding factors that should be acknowledged to avoid false conclusions. Purpose To investigate the possible effects of age, gender, smoking, alcohol consumption, and education on
Miina Nenonen, Ullamari Hakulinen, Antti Brander, Juha Ohman, Prasun Dastidar, Teemu M Luoto   +5 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

A Commentary on “Association Between Oral Behaviors and Painful Temporomandibular Disorders: A Cross-Sectional Study in the General Population” [Letter]

Journal of Pain Research
Junhao Fang,1,* Yanlin Wu,2,* Hongxuan Tong3,4 1Stomatology Grade 2022, School of Clinical Medicine, Hangzhou Normal University, Hangzhou, 311121, People’s Republic of China; 2Clinical Medicine Grade 2021, School of Clinical Medicine ...
Fang J, Wu Y, Tong H
doaj