Results 111 to 120 of about 762,252 (305)
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
24 weeks of Pilates-aerobic and educative training to improve body fat mass in elderly Serbian women
Clinical Interventions in Aging, 2014 Anne WS Rutjes,1 Marcello Di Nisio2,31Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland; 2Department of Medical, Oral, and Biotechnological Sciences, University G D'Annunzio of Chieti-Pescara, Chieti, Italy ...
Rutjes AWS, Di Nisio M
doaj
Health Science ReportsBackground and Aims Vitamin D deficiency is a common nutritional problem in women of childbearing age. Polycystic ovary syndrome (PCOS) is a frequent endocrine disorder associated with various metabolic complications.
Fatemeh Yari +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Additional Mendelian randomization analysis by eliminating confounding factors.
Additional Mendelian randomization analysis by eliminating confounding factors.
Jiajun Liu (692586) +6 more
core +1 more source
Variation caused by confounding factors.
, 2016 Selected samples to exemplify the influence of confounding factors (Table 2) derived from the PCA analysis of the complete experiment. Sample means are used except for D and E.
Annemieke de Vries (224578) +9 more
core +1 more source
Aging and Cancer, EarlyView.This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
Code to correct phenotypes and genotypes for confounding factors
, 2018 This is the R script that was used to correct the phenotypes and imputed genotypes for possible confounding factors prior to conducting Random Forest ...
Marine Brieuc (5010398) +15 more
core +1 more source