Results 91 to 100 of about 762,252 (305)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

A Review of Mendelian Randomization: Assumptions, Methods, and Application to Obesity-Related Diseases

open access: yesJournal of Obesity & Metabolic Syndrome
Mendelian randomization (MR) is a statistical method that uses genetic variants as instrumental variables to estimate the causal effect of exposure on an outcome in the presence of unmeasured confounding.
Seungjae Lee, Woojoo Lee
doaj   +1 more source

Iron overload and arrhythmias: Influence of confounding factors

open access: yesJournal of Arrhythmia, 2019
Arrhythmias as a cardiac complication of iron overload (IO) have been well described for decades in the clinical literature. They are assumed to be directly associated with the myocardial accumulation of iron.
Yukitaka Shizukuda, Douglas R. Rosing
doaj   +1 more source

Subgroup analysis according to the adjustment for significant confounding factors.

open access: yes, 2015
Subgroup analysis according to the adjustment for significant confounding factors.
Chengqing Yi (729812)   +3 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Curr Epidemiol Rep [PDF]

open access: yes
Purpose of review:Violence prevention research has enhanced our understanding of individual and community risk and protective factors for aggression and violence.

core  

Association between perioperative statin and delirium after potential confounding factors.

open access: yes, 2018
Association between perioperative statin and delirium after potential confounding factors.
Mi Yeon Lee (160306)   +5 more
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Role of confounding factors in assessing immune competence of bivalves (Mya arenaria, Mytilus edulis) exposed to pollutants

open access: yesJournal of Xenobiotics, 2013
Not ...
C. Brousseau-Fournier   +8 more
doaj   +1 more source

Effect of confounding factors on the set of samples analysed.

open access: yes, 2014
Effect of confounding factors on the set of samples analysed.
Kamalesh Dattaram Mumbrekar (530340)   +7 more
core   +1 more source

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