Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
A Pseudomonas aeruginosa AK6U strain produced rhamnolipid biosurfactants to variable extents when grown on MgSO4 or organosulfur compounds as sulfur sources and glucose as a carbon source. Organosulfur cultures produced much higher biosurfactants amounts
Wael Ismail +6 more
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Photoswitchable ORG25543 Congener Enables Optical Control of Glycine Transporter 2 [PDF]
Shannon N. Mostyn +7 more
openalex +1 more source
The Predatory Bird Monitoring Scheme (PBMS) Report 2006-7 [PDF]
The Predatory Bird Monitoring Scheme (PBMS) examines the levels of certain pollutants in selected wildlife species in Britain. It started in the 1960s to assess the impact of organochlorine pesticides on raptor populations, and the scheme is now the ...
Lawlor, A.J. +7 more
core
Three New Food Plants and First Wisconsin Record of \u3ci\u3ePublilia Reticulata\u3c/i\u3e (Hemiptera: Membracidae) [PDF]
Publilia reticulata was found feeding on the composites Silphium perfoliatum, S. integrifolium and Ambrosia trifida at eight sites in five Wisconsin counties in 1993-1995. This is the first report of P. reticulata using these plants and of its occurrence
Williams, Andrew H
core +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Profiling PBDE emissions from coastal landfills: Impact of waste management practices
This study investigates the influence of landfill management practices on the release of polybrominated diphenyl ethers (PBDEs) from coastal landfills in Newfoundland, Canada.
Priyam Saxena +4 more
doaj +1 more source
Studies on the profile of polychlorinated biphenyls congeners in bottom sediments of the Barents Sea
Novikov Mikhail A. +3 more
openalex +1 more source
Snoqualmia, a new polydesmid milliped genus from the northwestern United States, with a description of two new species (Diplopoda, Polydesmida, Polydesmidae) [PDF]
Snoqualmia, new genus, is described for two species of polydesmid millipeds from the northwestern United States: Snoqualmia snoqualmie, new species, from Washington State, and S. idaho, new species, from Idaho. Males of S.
Shear, William A.
core +2 more sources

