Results 181 to 190 of about 90,212 (381)

Evaluation of Polybrominated Diphenyl Ether Toxicity on HepG2 Cells – Hexabrominated Congener (BDE‐154) Is Less Toxic than Tetrabrominated Congener (BDE‐47)

Basic & Clinical Pharmacology & Toxicology, 2016
Alecsandra Oliveira Souza, M. Tasso, Alana M C Oliveira, L. C. Pereira, F. V. Duarte, D. Oliveira, C. Palmeira, D. J. Dorta   +7 more
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

The complete mitochondrial genome of Lacerta bilineata and comparison with its closely related congener L. Viridis

, 2015
Sree Rohit Raj Kolora, Rui Faria, Anne Weigert, Stefan Schaffer, Annegret Grimm‐Seyfarth, Klaus Henle, Abdullah H. Sahyoun, Peter F. Stadler, Katja Nowick, Christoph Bleidorn, Martin Schlegel   +10 more
openalex   +2 more sources

Quantitative analysis of 209 polychlorinated biphenyl (PCB) congeners in sediments of the Raritan River estuary, USA [PDF]

, 2020
Yanan Li, Jing Li, Zhiwei Shao, Zhihui Duan, Yu Xie, Zhitai Cui, Jingyuan Li, Haoyi Zhou, Mengjie Chen, Sicheng Li, Chengyu Chen   +10 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Total synthesis of nogalamycin congeners.

, 1990
Fuyuhiko Matsuda, Shiro Terashima
openalex   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Chlorinated Paraffins in Chicken Eggs from Five Regions in China and Dietary Exposure Health Risk Assessment. [PDF]

Toxics
Wu N, Zhang L, Zhou T, Weng J, Li C, Song W, Zhou Y, Li Q, Lu Y, Zhou P, Gao L.   +10 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Airborne PCB Concentrations in Portland, Oregon: Emissions and Contributions from the Portland Harbor Superfund Site. [PDF]

ACS EST Air
Slade AR, Martinez A, Mathieu-Campbell ME, Cohen C, Watkins SL, Hornbuckle KC.   +5 more
europepmc   +1 more source