Results 191 to 200 of about 90,212 (381)

A new entry to 1,2-benzenediol congeners.

, 1989
Y. OZAKI, Ikumi OSHIO, Sangwon Kim
openalex   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Assessment of Past Dioxin Emissions from Waste Incineration Plants Based on Archive Studies and Process Modeling: A New Methodological Tool. [PDF]

Arch Environ Contam Toxicol
Zhang X, de Aragao A, Moll-François F, Berthet A, Breider F.   +4 more
europepmc   +1 more source

Assessing human polychlorinated biphenyl contamination for epidemiologic studies: lessons from patterns of congener concentrations in Canadians in 1992.

, 2002
Beth C. Gladen, Josée Doucet, Larry G. Hansen   +2 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Occurrence, Homologue Profiles and Risk Assessment of Short- and Medium-Chain Chlorinated Paraffins in Edible Vegetable Oils. [PDF]

Foods
Lu Y, Wu N, Gao L, Zhang L, Zhou T, Cao P, Chen J, Zhou P.   +7 more
europepmc   +1 more source

Synthesis, Characterization, and Antimicrobial Evaluation of Oxadiazole Congeners [PDF]

, 2011
Bassem Sadek, Khairi Mustafa Fahelelbom
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Variation in tolerance to heterospecific pollen from a non-native congener depends on co-existence history of maternal and paternal source populations. [PDF]

Am J Bot
Hoshino Y, Horie S, Maki M, Dohzono I.
europepmc   +1 more source

Appendix H. Prevalence of co-occurring congeners: the Gentry data set.

, 2016
Colleen K. Kelly, Michael G. Bowler
openalex   +1 more source