Results 231 to 240 of about 90,212 (381)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A momentous progress update: epidermal growth factor receptor inhibitors as viable agents for combating cancer. [PDF]

RSC Med Chem
Jangra N, Sharma B, Kumar D, Kapoor A.
europepmc   +1 more source

Effects of two PBDE congeners on the moulting enzymes of the freshwater amphipod Gammarus pulex

, 2014
Éric Gismondi, Jean‐Pierre Thomé
openalex   +2 more sources

Subchronic inhalation exposure study of an airborne polychlorinated biphenyl mixture resembling the Chicago ambient air congener profile.

Environmental Science and Technology, 2012
Xin Hu, A. Adamcakova-Dodd, H. Lehmler, D. Hu, K. Hornbuckle, P. Thorne   +5 more
semanticscholar   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Concentrated Rhamnolipid Formulations: Bridging Chemodiversity to Structure, Flow Behavior, and Functionality. [PDF]

ACS Sustain Chem Eng
Tancredi M, Carandente Coscia C, Buonocore M, Cangiano A, Salvatore MM, Veronico L, Picone D, D'Ursi AM, Grimaldi M, Ottaviani MF, Guido S, Paduano L, Gentile L, D'Errico G.   +13 more
europepmc   +1 more source

Uncongenial congeners [PDF]

Nature, 2009
openaire   +1 more source

An invasive plant alters pollinator‐mediated phenotypic selection on a native congener [PDF]

, 2014
Carolyn Beans, Deborah A. Roach
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Environmental resistome-guided development of resistance-tolerant antibiotics. [PDF]

Proc Natl Acad Sci U S A
Peek J, Bhattacharjee A, Burian J, Hsieh DC, Hernandez Y, Ternei M, Panfil C, Brady SF.   +7 more
europepmc   +1 more source