Results 241 to 250 of about 90,212 (381)

Natural Rubrolides and Their Synthetic Congeners as Inhibitors of the Photosynthetic Electron Transport Chain

Milandip Karak, Jaime A. M. Acosta, Héctor F. Cortez-Hernandez, Johnny L. Cardona, Giuseppe Forlani, Luiz C. A. Barbosa   +5 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

BN/BO Doping of peri ‐Acenoacenes: Modulating Excited States in Trapeziumene Congeners [PDF]

Daniele Poletto, Mauro Marongiu, David Hernández‐Castillo, Rúben R. Ferreira, Martina Crosta, Pradip Kumar Mondal, Leticia González, Davide Bonifazi   +7 more
openalex   +1 more source

Effects of Salicylate and Its Noncalorigenic Congeners on the hyroidal Release of¹³¹I in Patients with Thyrotoxicosis1 [PDF]

, 1964
Kenneth A. Woeber, Russell M. Barakat, Sidney H. Ingbar   +2 more
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

1,3-bis(2,4,6-trinitrophenylaminooxy)propane and its 4-cyano-2,6-dinitrophenyl congener: Synthesis and properties

Open Chemistry, 2003
Covaci Irina, Ionita Petre, Caproiu Miron, Socoteanu Radu, Constantinescu Titus, Balaban Alexandru   +5 more
doaj   +1 more source

A niche-based framework for assessing invasion risks in related pest species with a case study. [PDF]

iScience
Zhang YJ, Qin S, Ji ML, Hu J, Wang J, Shi XD, Gong ZY, Ma FZ.   +7 more
europepmc   +1 more source

Design and Synthesis of Benzene Congeners of Resolvin E2, a Proresolving Lipid Mediator, as Its Stable Equivalents

, 2020
Yuto Murakami, Hayato Fukuda, Ryuta Muromoto, Koki Hirashima, Kohei Ishimura, Koichi Fujiwara, Jun Ishihara, Tadashi Matsuda, Mizuki Watanabe, Satoshi Shuto   +9 more
openalex   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Glucoselipid Biosurfactant Biosynthesis Operon of <i>Rouxiella badensis</i> DSM 100043^T: Screening, Identification, and Heterologous Expression in <i>Escherichia coli</i>. [PDF]

Microorganisms
Harahap AFP, Treinen C, Zyl LJV, Williams WT, Conrad J, Pfannstiel J, Klaiber I, Grether J, Hiller E, Vahidinasab M, Perino EHB, Lilge L, Burger A, Trindade M, Hausmann R.   +14 more
europepmc   +1 more source