Results 71 to 80 of about 401,716 (213)

Cumulative isotretinoin dosing, treatment response and acne relapse: A randomized controlled trial

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In this randomized controlled trial, cumulative isotretinoin doses of 120 and 150 mg/kg showed similar relapse rates at 12 months. Both regimens achieved substantial and comparable reductions in inflammatory acne lesions across the face, chest and back.
Ruggero Cascio Ingurgio, Angela Alfano, Antonio Costanzo, Julie S. Cronk, Rebecca Cummins, Benjamin S. Daniel, Ben J. Koszegi, Linda K. Martin, Clarisse G. Mendoza, Mae Ramirez‐Quizon, Lesley M. Rhodes, Heather I. Rishel, Adam I. Rubin, Fanny Satgé, Supriya Venugopal, Anna Wilson, Dedee F. Murrell   +16 more
wiley   +1 more source

Normal sex differences in prenatal growth and abnormal prenatal growth retardation associated with 46,XY disorders of sex development are absent in newborns with congenital adrenal hyperplasia due to 21-hydroxylase deficiency

Biology of Sex Differences, 2011
Background Congenital adrenal hyperplasia due to 21-hydroxylase deficiency is the most common presentation of a disorder of sex development (DSD) in genetic females. A report of prenatal growth retardation in cases of 46,XY DSD, coupled with observations
Chalmers Laura J, Doherty Paul, Migeon Claude J, Copeland Kenneth C, Bright Brianna C, Wisniewski Amy B   +5 more
doaj   +1 more source

GNAS mutation is an unusual cause of primary adrenal insufficiency: a case report

BMC Pediatrics, 2022
Background Primary adrenal insufficiency in children has non-specific and extensive clinical features, so the diagnosis of its etiology is complex and challenging.
Yajie Tong, Dongmei Yue, Ying Xin, Dan Zhang   +3 more
doaj   +1 more source

Associations between diet quality and adult acne: A cross sectional study in the UK Biobank

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Mediterranean‐style diet adherence was associated with lower odds of adult acne, particularly in women. In men, a low‐carbohydrate, high‐meat dietary pattern showed higher odds. Cooked vegetables and yoghurt were inversely associated, whereas pork, skimmed milk and milk‐based desserts showed positive associations.
Bochen Li, Yifan Xu, Ruotong Zhang, Alex Dregan, Rachel Gibson, Thivi Maruthappu, Christopher E. M. Griffiths, Wendy L. Hall   +7 more
wiley   +1 more source

The role of primary cilia and sonic hedgehog signalling in adrenal development function. [PDF]

, 2012
PhDPrimary cilia are sensory organelles found on most vertebrate cells during interphase. They play key roles in development, cell signalling and cancer, and are involved in signal transduction pathways such as Hh and Wnt signalling.
Cogger, Kathryn
core   +4 more sources

Risk and outcomes of adrenal crisis in primary adrenal insufficiency: Evidence from a 24‐year nationwide cohort study

Journal of Internal Medicine, EarlyView.
Abstract Background Adrenal crisis is a life‐threatening emergency. Despite preventive strategies, previous reports suggest increasing incidence and substantial mortality, but robust validated data are limited. Objective To assess temporal trends in adrenal crisis incidence and identify associated risk factors.
Ann‐Elin Meling Stokland, Lars Breivik, Ingvild Dalen, Sandra Dis Steintorsdottir, Simon Kildal, Ingrid Nermoen, Kari Lima, Margrethe Svendsen, Åse Bjorvatn Sævik, Aleksandra Debowska, Stina Therese Sollid, Daniel Hannisdal, Trine Elisabeth Finnes, Agnes Judit Horvath, Elin Korsgaard, Hallvard Singsås, Bjørn O. Åsvold, Maria Eriksson Steigen, Sigrid Blika, Petya Milova, Anders Svare, Anja Fog Heen, Lene Katrine Bjerke, Marianne Stedje, Siri Carlsen, Bjørn Gunnar Nedrebø, Anders Palmstrøm Jørgensen, Grethe Å. Ueland, Marianne Øksnes, Eystein Sverre Husebye   +29 more
wiley   +1 more source

Non-Virilizing Congenital Adrenal Hyperplasia in a Female Patient with a Novel HSD3B2 Mutation. [PDF]

, 2016
Classic 3β-hydroxysteroid dehydrogenase type 2 (3β-HSD II) deficiency causes congenital adrenal hyperplasia with glucocorticoid, mineralocorticoid, and sex steroid deficiency.
Udhane, Sameer S, Probst-Scheidegger, Ursina, Camats Tarruella, Núria, l'Allemand, Dagmar, Flück, Christa Emma   +4 more
core   +2 more sources

Co-existence of Congenital Adrenal Hyperplasia and Familial Hypokalemic Periodic Paralysis due to CYP21A2 and SCN4A Pathogenic Variants [PDF]

, 2021
Steroid 21-hydroxylase deficiency is the most common cause of congenital adrenal hyperplasia (CAH), usually due to biallelic variants in CYP21A2. Classical 21-hydroxylase deficiency is characterised by virilisation of the external genitalia in females ...
Tuğba Kontbay, İhsan Turan
core   +1 more source

Recent advances in polyendocrine metabolic ovarian syndrome, formerly polycystic ovary syndrome, with emphasis on endocrine and metabolic dysfunction and cardiovascular risk

Journal of Internal Medicine, EarlyView.
Abstract Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%–13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introduction of the new PMOS nomenclature in 2026 reflects a fundamental shift in understanding the condition as a lifelong endocrine ...
Maria Forslund, Johanna Melin, Anju E. Joham, Terhi T. Piltonen, D. Aled Rees, Helena J. Teede   +5 more
wiley   +1 more source

Modeling Congenital Adrenal Hyperplasia and Testing Interventions for Adrenal Insufficiency Using Donor-Specific Reprogrammed Cells

Cell Reports, 2018
Summary: Adrenal insufficiency is managed by hormone replacement therapy, which is far from optimal; the ability to generate functional steroidogenic cells would offer a unique opportunity for a curative approach to restoring the complex feedback ...
Gerard Ruiz-Babot, Mariya Balyura, Irene Hadjidemetriou, Sharon J. Ajodha, David R. Taylor, Lea Ghataore, Norman F. Taylor, Undine Schubert, Christian G. Ziegler, Helen L. Storr, Maralyn R. Druce, Evelien F. Gevers, William M. Drake, Umasuthan Srirangalingam, Gerard S. Conway, Peter J. King, Louise A. Metherell, Stefan R. Bornstein, Leonardo Guasti   +18 more
doaj   +1 more source