ABSTRACT Background Historically, bilateral pulmonary artery band (PAB) placement was guided by pulmonary blood flow surrogates including systemic blood pressure (BP) and arterial saturation. These metrics alone may result in suboptimal bPAB placement.
Jonathan Pacella+8 more
wiley +1 more source
Aims No curative treatment is available for RASopathy‐associated childhood‐onset hypertrophic cardiomyopathy (RAS‐CM). Preclinical data and individual reports suggest a beneficial effect of small molecules targeting the RAS–mitogen‐activated protein (MAP)
Jules Hamers+11 more
doaj +1 more source
Functional characterization of a novel PBX1 de novo missense variant identified in a patient with syndromic congenital heart disease. [PDF]
Pre-B cell leukemia factor 1 (PBX1) is an essential developmental transcription factor, mutations in which have recently been associated with CAKUTHED syndrome, characterized by multiple congenital defects including congenital heart disease (CHD). During
Alankarage, Dimuthu+9 more
core +1 more source
Szemléletváltozás a Down-szindrómás szívbetegek szívsebészeti kezelésében, 1974–2016 | Change in our approach in the surgical management of congenital heart defects in patients with Down syndrome, 1974–2016 [PDF]
Absztrakt Bevezetés: Down-szindrómás betegeknél gyakori a veleszületett szívfejlődési rendellenesség. Célkitűzés: A szerzők megvizsgálták, hogy a szívsebészetben bekövetkező szemléletváltozások ...
Bogáts, Gábor, Hartyánszky, István
core +1 more source
Dynamics of primary cilia in endothelial and mesenchymal cells throughout mouse lung development
Abstract Cilia are specialized structures found on a variety of mammalian cells, with variable roles in the transduction of mechanical and biological signals (by primary cilia, PC), as well as in the generation of fluid flow (by motile cilia). Their critical role in the establishment of a left–right axis in early development is well described, as well ...
Stephen Spurgin+8 more
wiley +1 more source
Incidence and Types of Congenital Heart Diseases among Children in Sulaimani Governorate
Congenital heart diseases (CHD) are common causes of cardiovascular morbidity and mortality among young children and adolescents. It is the most common form of structural congenital defects.
Niaz Kamal, Nasih Othman, Aso Salih
doaj +1 more source
Procollagen IIA Deficient Mice [PDF]
This invention relates to the production of dual models of Congenital Heart Defects and Hypertrophic Cardiomyopathy with the use of mice which are genetically modified by transgenic (gene-knockout) techniques. The present invention produces knockout mice
core
Swiss Adult Congenital HEart disease Registry (SACHER) - rationale, design and first results. [PDF]
In 2013, a prospective registry for adults with congenital heart disease (CHD) was established in Switzerland, providing detailed data on disease characteristics and outcomes: Swiss Adult Congenital HEart disease Registry (SACHER).
Attenhofer Jost, C.+16 more
core +1 more source
Congenital Heart Defects in Chick Embryos Subjected to Temperature Variations [PDF]
María V. de la Cruz+4 more
openalex +1 more source
Sudden unexpected death in children with congenital heart defects.
AIMS Congenital heart defects (CHDs) are the most common birth defects and are an important cause of death in children. The fear of sudden unexpected death has led to restrictions of physical activity and competitive sports.
J. Jortveit+9 more
semanticscholar +1 more source