Results 141 to 150 of about 355,187 (399)

Acute kidney injury and morbi‐mortality associated with “triple whammy” combination: Systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims “Triple whammy” (TW) refers to the concomitant use of diuretics, renin‐angiotensin‐aldosterone system inhibitors (RAASI) and non‐steroidal anti‐inflammatory drugs (NSAIDs). The aim of this article is to analyse the association between TW exposure and acute kidney injury (AKI), among other morbi‐mortality outcomes.
Dulce María Calvo   +4 more
wiley   +1 more source

Cytomegalovirus infection and congenital heart disease in children

open access: yesЖурнал инфектологии, 2019
Congenital heart defects account for about 30% of all anomaly of development in children. Cytomegalovirus infection suffered by a woman during pregnancy claims one of the leading places among teratogenic factors.Aim: to study clinical and pathogenetic ...
E. A. Каshuba   +6 more
doaj   +1 more source

Prevalence and predictors of later feeding disorders in children who underwent neonatal cardiac surgery for congenital heart disease [PDF]

open access: yes, 2017
Aim We thought of assessing the prevalence and predictors of feeding disorders in patients with congenital heart defects after neonatal cardiac surgery.
Balmer, Christian   +5 more
core  

Perventricular Device Closure of Native Congenital Muscular Ventricular Septal Defects in Small Infants   $\hspace{0.17em}$ ≤ 5 kg: Single‐Center Study of the Risk Factors for Failure of the Intervention and Non‐Optimal Outcome

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background and Aims Perventricular device closure of muscular VSD in small infants is a less invasive option than surgical closure under cardiopulmonary bypass and offers better outcomes than palliative pulmonary artery banding. However, the specific risk factors that could affect procedural success and optimal outcomes have not been ...
Emine Hekim Yilmaz   +7 more
wiley   +1 more source

Honeycomb or Lotus Root‐Like Intracoronary Pattern: Insights From Optical Coherence Tomography of a Recanalized Thrombus

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Spontaneous recanalized coronary thrombus (SRCT) has been identified in autopsy studies as multiple interconnected channels separated by thin septa. Despite its potential clinical significance, SRCT remains underdiagnosed. Recent advances in intracoronary imaging, including optical coherence tomography (OCT), have elucidated its ...
Fernando Quevedo   +9 more
wiley   +1 more source

Dynamics of primary cilia in endothelial and mesenchymal cells throughout mouse lung development

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Cilia are specialized structures found on a variety of mammalian cells, with variable roles in the transduction of mechanical and biological signals (by primary cilia, PC), as well as in the generation of fluid flow (by motile cilia). Their critical role in the establishment of a left–right axis in early development is well described, as well ...
Stephen Spurgin   +8 more
wiley   +1 more source

Trametinib alters contractility of paediatric Noonan syndrome‐associated hypertrophic myocardial tissue slices

open access: yesESC Heart Failure
Aims No curative treatment is available for RASopathy‐associated childhood‐onset hypertrophic cardiomyopathy (RAS‐CM). Preclinical data and individual reports suggest a beneficial effect of small molecules targeting the RAS–mitogen‐activated protein (MAP)
Jules Hamers   +11 more
doaj   +1 more source

Identification of novel genes regulating the development of the palate

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley   +1 more source

Effects of Pax3 mutation and Neural Crest genetic ablation on congenital heart function and embryonic lethality [PDF]

open access: yes, 2011
poster abstractCongenital heart defects (CHDs) occur in approximately one percent of births every year (American Heart Association, 2008). This makes it the most frequently occurring congenital defect in humans.
Chikaraishi, Dona M.   +4 more
core  

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