Results 111 to 120 of about 3,896,028 (254)

Rehabilitation program in adult congenital heart disease patients with pulmonary hypertension

open access: yes, 2010
Introduction. It is commonly believed that physical activity may have a negative impact on pulmonary hypertension patients. The object of this study is to determine the tolerability of a directed exercise program in congenital heart disease patients with
Miranda Calderín, Guillermo   +7 more
core   +1 more source

CYP3A5 genetic variability influences sildenafil and metabolite in pulmonary hypertension

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Interindividual variability in sildenafil response among pulmonary hypertension patients (PH) may be influenced by CYP3A5 polymorphisms. CYP3A5*3 allele reduces CYP3A5 activity and affects sildenafil metabolism. This study investigated the associations between CYP3A5 genotype and plasma concentrations of sildenafil and N‐desmethyl sildenafil, as ...
Pranisa Wongwien   +7 more
wiley   +1 more source

Optimized micro‐sized cell sphere‐matrix niche co‐aggregates promote efficient oral and craniomaxillofacial bone regeneration

open access: yesBMEMat, EarlyView.
The construct of cell‐niche co‐aggregates (GelMA‐SHED sphere‐DDMPs) promotes cranial and periodontal bone regeneration and ensures angiogenic‐osteogenic coupling by downregulating miR‐34c‐5p to enhance the expression of NOTCH1 and its intracellular domain (NICD).
Xiao‐Hui Zhang   +23 more
wiley   +1 more source

Stepwise evaluation of left to right shunts by echocardiography

open access: yesIndian Heart Journal, 2013
Neeraj Awasthy, S. Radhakrishnan
doaj   +1 more source

Prognostic Value of Serial Risk Stratification in Adult and Pediatric Pulmonary Arterial Hypertension: A Systematic Review

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background In pulmonary arterial hypertension, it is recommended to base therapeutic decisions on risk stratification. This systematic review aims to report the prognostic value of serial risk stratification in adult and pediatric pulmonary arterial ...
Chantal Lokhorst   +3 more
doaj   +1 more source

Style of Coping and its Determinants in Adults with Congenital Heart Disease in a Developing Country

open access: yes, 2014
Objective The objective of this study is to compare coping strategies between adults with and without congenital heart disease and to scrutinize the associations between different available resources (e.g., social support) and adoption of certain coping ...
Soares, Joaquim J. F.,   +6 more
core   +1 more source

The Incidence, Severity and Clinical Consequence of Left Pulmonary Artery Stenosis After PDA Device Closure in Premature Infants Less Than 2 Kilograms

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Transcatheter patent ductus arteriosus (PDA) device closure is an effective treatment option for premature infants with hemodynamically significant PDA. Left pulmonary artery (LPA) stenosis has been reported as a complication, however there is limited data on risk factors, clinical significance, and long‐term outcomes.
Bryan Mosher   +7 more
wiley   +1 more source

Management of grown up congenital heart disease

open access: yes, 2003
s a result of the success of paediatric cardiology and cardiac surgery over the last three decades, there will shortly be more adults than children with congenital heart disease.
Alonso MA   +37 more
core  

Association of congenital heart diseases with extracardiac anomalies

open access: yes, 2017
Background: Congenital heart diseases are one of the main causes of death among the congenital malformations. An extracardiac malformation further increases the risk of morbidity and mortality to these patients, in addition to risks of surgical ...
Mithlesh Dewangan
core   +1 more source

Impaired Flow and Physiology in Coronaries With Anomalous Origin From the Opposite Sinus of Valsalva

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Anomalous Aortic Origin of a Coronary Artery (AAOCA) high‐risk anatomical features (intramural segment, acute take‐off angle, slit‐like ostium) cause coronary stenosis leading to myocardial infarction. How these features alter coronary physiology remains unclear.
Mauro Lo Rito   +17 more
wiley   +1 more source

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