Pediatric pulmonary hypertension [PDF]
Pulmonary hypertension (PH) can present at any age from the neonatal period to adulthood. Pediatric PH is similar to adults but differentiates itself as in a growing child the lungs are still developing (1). It is a hemodynamic condition defined by an increased pulmonary artery mean pressure above or equal to 25 mmHg (1).
Maurice eBeghetti, Frederic eLador
doaj +5 more sources
A Canadian, retrospective, multicenter experience with selexipag for a heterogeneous group of pediatric pulmonary hypertension patients [PDF]
IntroductionSelexipag, an oral nonprostanoid prostaglandin receptor agonist, has led to reduced morbidity and mortality in adults with pulmonary arterial hypertension (PAH). While the adult literature has been extrapolated to suggest selexipag as an oral
David Youssef +9 more
doaj +2 more sources
Case Report: Selexipag in pediatric pulmonary hypertension: Initiation, transition, and titration [PDF]
Selexipag, a selective prostacyclin receptor agonist, is approved for treating pulmonary arterial hypertension in WHO Group 1 adult patients. Compared to parenteral prostacyclin formulations, selexipag offers a significant improvement in patient’s and ...
Jenna M. Faircloth +10 more
doaj +2 more sources
Treatment of pediatric pulmonary hypertension
Amy Hawkins, Robert TullohDepartment of Congenital Heart Disease, Bristol Royal Hospital for Children, Bristol UKAbstract: Pulmonary hypertension was once thought to be a rare condition and only managed in specialized centers.
Amy Hawkins, Robert Tulloh
doaj +6 more sources
Echocardiography in pediatric pulmonary hypertension [PDF]
Pulmonary hypertension (PH) can be a rapidly progressive and fatal disease. Although right heart catheterization remains the gold standard in evaluation of PH, echocardiography remains an important tool in screening, diagnosing, evaluating, and ...
Pei-Ni eJone, D. Dunbar eIvy
doaj +3 more sources
Pediatric pulmonary hypertension.
Pulmonary hypertension (PH) is a rare disease in newborns, infants, and children that is associated with significant morbidity and mortality. In the majority of pediatric patients, PH is idiopathic or associated with congenital heart disease and rarely is associated with other conditions such as connective tissue or thromboembolic disease.
Maurice Beghetti, Steven Abman
exaly +7 more sources
Building a dedicated pediatric pulmonary hypertension program: A consensus statement from the pediatric pulmonary hypertension network [PDF]
Pediatric pulmonary hypertension (PH) is a severe, life‐threatening disease associated with diverse cardiac, pulmonary, and systemic disorders, which generally requires expertise from multiple disciplines for management. Unfortunately, expert centers are
Stephanie S. Handler +12 more
doaj +2 more sources
Racial and Ethnic Differences in Pediatric Pulmonary Hypertension: An Analysis of the Pediatric Pulmonary Hypertension Network Registry [PDF]
To investigate racial and ethnic differences in pulmonary hypertension subtypes and survival differences in a pediatric population.This was a retrospective analysis of a cohort of patients with pulmonary hypertension (aged ≤18 years) enrolled in the Pediatric Pulmonary Hypertension Network registry between 2014 and 2018, comprising patients at eight ...
Mary Mullen +2 more
exaly +3 more sources
Current Challenges in Pediatric Pulmonary Hypertension [PDF]
Pulmonary arterial hypertension (PAH) in the pediatric population is associated with a variety of underlying diseases and causes, significantly morbidity and mortality. In the majority of patients, PAH in children is idiopathic or associated with congenital heart disease (CHD), with pulmonary hypertension (PH) associated with connective tissue disease,
Shinichi Takatsuki, Dunbar Ivy
exaly +3 more sources
Persistent Challenges in Pediatric Pulmonary Hypertension [PDF]
Pulmonary hypertension and related pulmonary vascular diseases cause significant morbidities and high mortality and present many unique challenges toward improving outcomes in neonates, infants, and children. Differences between pediatric and adult disease are reflected in controversies regarding etiologies, classification, epidemiology, diagnostic ...
Steven Abman, Rachel K Hopper
exaly +3 more sources

