Results 11 to 20 of about 5,557 (240)

Clinical Presentation of Congenital Hypopituitarism: Lessons From a Large Academic Centre. [PDF]

Clin Endocrinol (Oxf)
ABSTRACT Objective Pituitary hormone deficiencies are associated with considerable morbidity, yet the variability of presentation and evolution of congenital hypopituitarism remains unexplored. This study investigated differences in presentation of congenital isolated pituitary hormone deficiency (cIPHD) versus congenital multiple pituitary hormone ...
Ladd JM, Pyle-Eilola AL, Mamilly L, Chaudhari M, Henry RK.   +4 more
europepmc   +3 more sources

Evidence That the Etiology of Congenital Hypopituitarism Has a Major Genetic Component but Is Infrequently Monogenic. [PDF]

Front Genet, 2021
PurposeCongenital hypopituitarism usually occurs sporadically. In most patients, the etiology remains unknown.MethodsWe studied 13 children with sporadic congenital hypopituitarism. Children with non-endocrine, non-familial idiopathic short stature (NFSS)
Jee YH, Gangat M, Yeliosof O, Temnycky AG, Vanapruks S, Whalen P, Gourgari E, Bleach C, Yu CH, Marshall I, Yanovski JA, Link K, Ten S, Baron J, Radovick S.   +14 more
europepmc   +4 more sources

Adult Cirrhosis Due to Untreated Congenital Hypopituitarism [PDF]

Journal of the Royal Society of Medicine, 2005
Hypopituitarism is a diagnosis to be considered in unexplained neonatal hepatitis.1-3 Little is known about the possibility of long-term liver damage.
M Keston Jones, Narinder Kochar, Aye Nyunt, Daniella T Pilz, Jeremy G C Kingham   +4 more
openaire   +4 more sources

Anterior pituitary hormone effects on hepatic functions in infants with congenital hypopituitarism

Annals of Hepatology, 2007
Background: Congenital hypopituitarism is an uncommon cause of neonatal cholestasis. Little is known about the effect of anterior pituitary hormone on hepatic functions.Methods: A retrospective review of the medical charts of eight infants with ...
Wikrom Karnsakul;, Pairunyar Sawathiparnich;, Saroj Nimkarn;, Supawadee Likitmaskul;, Jeerunda Santiprabhob;, Prapun Aanpreung   +5 more
doaj   +2 more sources

Congenital Hypopituitarism due to POU1F1 Gene Mutation

Journal of the Formosan Medical Association, 2011
POU1F1 (Pit-1; Gene ID 5449) is an anterior pituitary transcriptional factor, and POU1F1 mutation is known to cause anterior pituitary hypoplasia, growth hormone and prolactin deficiency and various degree of hypothyroidism. We report here a patient who presented with growth failure and central hypothyroidism since early infancy.
Wen-Yu Tsai, Yi-Ching Tung, Yin-Hsiu Chien, Ni-Chung Lee, Shinn-Forng Peng, Wuh-Liang Hwu   +5 more
openaire   +4 more sources

Congenital hypopituitarism: Monitoring after coronary artery bypass grafting

Annals of Cardiac Anaesthesia, 2010
Cardiovascular disease in patients with congenital hypopituitarism is not rare; however, there is a lack of reports referring to cardiac interventions in such patients.
Siminelakis Stavros, Kotsanti Angeliki, Baikoussis Nikolaos, Andrikoula Maria, Bairaktari Eleni, Papadopoulos George   +5 more
doaj   +2 more sources

Three Japanese patients with congenital pituitary hormone deficiency and ophthalmological anomalies [PDF]

Pediatric Reports, 2011
The clinical phenotype of congenital pituitary hormone deficiency is variable and can be associated with a number of structural abnormalities of the central nervous system.
Katsura, Ishizu, Nagashima, Tetsuro, Nakamura, Akie, Nakanishi, Masanori, Noro, Ayumu, Sugiyama, Minako, Suzuki, Yashuto, Tajima, Toshihiro, Takanashi, Kuniko   +8 more
core   +5 more sources

Abnormal cognitive function in treated congenital hypopituitarism [PDF]

Archives of Disease in Childhood, 2004
To assess cognitive function in school age children with congenital pituitary hormone deficiency (PHD).Ten children with PHD (aged 6.0-15.6 years, mean 11.5 years) and sibling controls (aged 8.7-14.9 years, mean 12.1 years) were assessed using the Wechsler Intelligence Scale for Children (WISC-III UK).The patients' full scale IQ scores were all below ...
Brown K, Rodgers J, Johnstone H, Adams W, Clarke M, Gibson M, Cheetham T   +6 more
openaire   +6 more sources

Cholestasis syndrome in a newborn child with congenital hypopituitarism

Russian Pediatric Journal, 2021
The purpose of the work is comprehensive examination of a newborn with cholestasis syndrome to determine congenital hypopituitarism. Materials and methods. The child was hospitalized on the 30th day of his life. At admission, complaints were noted about the ictericity of the skin, low body weight gain, convulsive syndrome (history).
Nataliya A. Kharitonova, Milana A. Basargina, Khadizhat S. Evloeva   +2 more
openaire   +2 more sources

Heterozygous defects in PAX6 gene and congenital hypopituitarism [PDF]

European Journal of Endocrinology, 2015
BackgroundThe prevalence of congenital hypopituitarism (CH) attributable to known transcription factor mutations appears to be rare and other causative genes for CH remain to be identified. Due to the sporadic occurrence of CH,de novochromosomal rearrangements could be one of the molecular mechanisms participating in its etiology, especially in ...
Yukihiro Hasegawa, Tomonobu Hasegawa, Yumi Asakura, Ikuma Fujiwara, Koji Muroya, Masaki Takagi, Masanori Adachi, Naoko Amano, Tomohiro Ishii, Keisuke Nagasaki   +9 more
openaire   +4 more sources