Results 21 to 30 of about 265,208 (194)

Cancerous leptomeningitis and familial congenital hypopituitarism

Endocrine, 2016
People are at higher risk of cancer as they get older or have a strong family history of cancer. The potential influence of environmental and behavioral factors remains poorly understood. Earlier population and case control studies reported that upper quartile of circulating IGF-I is associated with a higher risk of developing cancer suggesting ...
Vujovic, S., Vujosevic, S., Kavaric, S., Sopta, J., Ivovic, M., Saveanu, Alexandru, Brue, Thierry, Korbonits, M., Popovic, V.   +8 more
openaire   +4 more sources

"CONGENTIAL PANHYPOPITUITARISM ASSOCIATED WITH IMPAIRED LIVER FUNCTION TESTS AND CONGENITAL HEART DISEASE" [PDF]

Acta Medica Iranica, 2006
The term congenital hypopituitarism defines deficiency of all of the pituitary hormones. Hypoglycemia and microphallus (in males) are common findings, and some infants have shown evidence of the neonatal hepatitis syndrome. We report a case of congenital
Z. Khalili-Matinzadeh
doaj   +3 more sources

[Congenital hypopituitarism with monosomy of chromosome 18]. [PDF]

Probl Endokrinol (Mosk), 2021
Congenital hypopituitarism is a rare disease. It can be caused by isolated inborn defects of the pituitary, gene mutations (PROP1, PIT1), and chromosomal abnormalities.Deletions of chromosome 18 (De Grouchy syndrome types 1 and 2) are a group of rare genetic diseases with a frequency of 1:50,000.
Bolmasova AV, Melikyan MA, Gadzhieva ZS, Puchkova AA, Degtyareva AV, Peterkova VA.   +5 more
europepmc   +4 more sources

Severe hepatopulmonary syndrome with end-stage liver cirrhosis associated with pan-hypopituitarism in a pediatric patient

Journal of Clinical and Translational Endocrinology Case Reports
Cholestasis in the neonatal period requires a prompt and thorough evaluation. Panhypopituitarism is an uncommon but known cause of cholestasis. Here we present a rare and late complication of liver disease secondary to congenital hypopituitarism ...
Shawn A. Haupt, Jessica C. Chang, Roya Zarpak, Arash R. Zandieh, Nada A. Yazigi, Udeme D. Ekong, Juan F. Guerra, Thomas M. Fishbein, Cal S. Matsumoto, Alexander H. Kroemer, Khalid M. Khan   +10 more
doaj   +2 more sources

Generation of an iPSC line from congenital hypopituitarism patient with a nonsense heterozygous variant in FOXA2

Stem Cell Research
Forkhead box A2 (FOXA2) is a pioneer transcription factor, necessary for human development. Mutations in FOXA2 were recently associated with congenital hypopituitarism (CH); however, the pathogenic mechanism remains unknown.
Camilletti Maria Andrea, Chirino Felker Gonzalo Tomás, Castañeda Sheila, Zabalegui Federico, Amin Guadalupe, Belgorosky Alicia, Ciaccio Marta, Di Palma Maria Isabel, Vaiani Elisa, Waisman Ariel, Miriuka Santiago, Pérez Millán María Inés, Moro Lucia Natalia   +12 more
doaj   +2 more sources

Congenital hypopituitarism in two brothers with a duplication of the 'acrogigantism gene' GPR101: clinical findings and review of the literature. [PDF]

Pituitary, 2021
Purpose: Congenital hypopituitarism (CH) can cause significant morbidity or even mortality. In the majority of patients, the etiology of CH is unknown.
Elizabeth MSM, Verkerk AJMH, Hokken-Koelega ACS, Verlouw JAM, Argente J, Pfaeffle R, Neggers SJCMM, Visser JA, de Graaff LCG.   +8 more
europepmc   +2 more sources

Pituitary Stalk Interruption Syndrome: A Case Report

Turkish Journal of Internal Medicine, 2021
Panhypopituitarism occurs as a result of the insufficiency of all hormones produced in the anterior pituitary gland. Pituitary Stalk Interruption Syndrome (PSIS) is a rare congenital syndrome leading to hypopituitarism.
Yasemin Aydoğan Ünsal, Ensar Aydemir, Merve Nur Akyol, Coşkun Ateş, Soner Cander, Özen Öz Gül, Erdinç Ertürk, Canan Ersoy   +7 more
doaj   +1 more source

Prolonged neonatal hyperbilirubinaemia in a case of congenital hypopituitarism. [PDF]

BMJ Case Rep, 2019
A 2-month-old girl presented with prolonged neonatal jaundice along with progressive abdominal distension and intermittent passage of hard stools. There was no history of high coloured urine, clay coloured stool, poor feeding, lethargy or high-pitched cry.
Bhattacharya D, Kumar R, Kumar R, Dayal D.   +3 more
europepmc   +4 more sources

Congenital hypopituitarism: A case report

Journal of Oral Medicine, Oral Surgery, Oral Pathology and Oral Radiology, 2021
Congenital hypopituitarism can be life threatening in neonates while its early diagnosis is a greater challenge for the dentist. Hypopituitarism can result from diseases of the hypothalamus or of the pituitary gland. In adults it is often missed due to its nonspecific symptoms of growth hormone deficiency hence early diagnosis and prompt treatment is ...
Milan Singh Mali, Krishna Priya Vllr, Gaddam Shilpa, Ch. Santosh Kumar   +3 more
openaire   +1 more source

Table_1_Evidence That the Etiology of Congenital Hypopituitarism Has a Major Genetic Component but Is Infrequently Monogenic.DOCX

, 2021
PurposeCongenital hypopituitarism usually occurs sporadically. In most patients, the etiology remains unknown.MethodsWe studied 13 children with sporadic congenital hypopituitarism. Children with non-endocrine, non-familial idiopathic short stature (NFSS)
Adrian G. Temnycky (11260872), Jack A. Yanovski (7542557), Kathleen Link (11260887), Mariam Gangat (11260866), Evgenia Gourgari (6526040), Olga Yeliosof (11260869), Svetlana Ten (11260890), Sally Radovick (703416), Philip Whalen (11260878), Christine H. Yu (11260884), Selena Vanapruks (11260875), Cortney Bleach (11260881), Ian Marshall (287669), Youn Hee Jee (7542533), Jeffrey Baron (516003)   +14 more
core   +1 more source