Results 21 to 30 of about 8,700 (250)

A challenging diagnosis of chronic osteomyelitis in a child with congenital insensitivity to pain: a case report. [PDF]

Ann Med Surg (Lond)
Kamil H, Alassri R, Albelal D, Alassri AB, Martini N, Mahmod J.   +5 more
europepmc   +2 more sources

Congenital insensitivity to pain [PDF]

The Journal of Bone and Joint Surgery. British volume, 2002
We reviewed 13 patients with congenital insensitivity to pain. A quantitative sweat test was carried out in five and an intradermal histamine test in ten. DNA examination showed specific mutations in four patients. There were three clinical presentations: type A, in which multiple infections occurred (five patients); type B, with fractures, growth ...
E, Bar-On, D, Weigl, R, Parvari, K, Katz, R, Weitz, T, Steinberg   +5 more
openaire   +2 more sources

Case report of a 7-year-old CIPA child with multiple debridement's and amputations.

International Journal of Endorsing Health Science Research, 2021
Background: Congenital Insensitivity to Pain (CIPA), otherwise known as Hereditary Sensory and Autonomic Neuropathy Type IV (HSAN IV), is a rarely occurring autosomal recessive disorder encompassed by a group of hereditary and sensory autonomic ...
Syed Ali Haider Zaidi, Sufyan Razak, Syeda Kiran Fatima, Hafiz Abdul Wase, Syed Mohammad Haider Zaidi, Zeeshan Yousuf, Farah Naz, Bilal Yousuf   +7 more
doaj   +1 more source

Congenital insensitivity to pain with anhidrosis: a literature review and the advocacy for stem cell therapeutic interventions. [PDF]

Ther Adv Rare Dis
Ikrama M, Usama M, Haider MH, Israr S, Humayon M.   +4 more
europepmc   +2 more sources

A Systematic Review of Congenital Insensitivity to Pain, a Rare Disease [PDF]

J Pers Med
Rodríguez-Blanque R, Nielsen L, Piqueras-Sola B, Sánchez-García J, Cortés-Martín C, Reinoso-Cobo A, Cortés-Martín J.   +6 more
europepmc   +3 more sources

Clinical features for diagnosis and management of patients with PRDM12 congenital insensitivity to pain. [PDF]

, 2016
BACKGROUND: Congenital insensitivity to pain (CIP) is a rare extreme phenotype characterised by an inability to perceive pain present from birth due to lack of, or malfunction of, nociceptors.
Ahmed, Mushtaq, Bennett, Christopher, Chen, Ya-Chun, Sharif, Saghira Malik, Sheridan, Eamonn, Valente, Enza-Maria, Woods, Geoffrey, Zhang, Stella   +7 more
core   +9 more sources

Phenotypes and Genotypes in Five Children with Congenital Insensitivity to Pain with Anhidrosis

Pediatric Neurology, 2016
Qing-Li Wang, Shanna Guo, Guangyou Duan, Ying Ying, Penghao Huang, Jing Yu Liu, Xianwei Zhang   +6 more
openalex   +3 more sources

Can We Share a Pain We Never Felt? Neural Correlates of Empathy in Patients with Congenital Insensitivity to Pain [PDF]

Neuron, 2009
Nicolas Danziger, Isabelle Faillenot, Roland Peyron   +2 more
openalex   +3 more sources

Congenital Insensitivity to Pain with Anhidrosis (CIPA) Syndrome; A Rare Genetic Disorder Case Story

Case Reports in Clinical Practice, 2022
Congenital insensitivity to pain with anhidrosis (CIPA) is the subtype four of hereditary sensory and autonomic neuropathy (HASN IV), caused by a defect in the NTRK1 gene and presenting early in life.
Zahra Nafei, Marjan Jafari
doaj   +1 more source

Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation

Cell Reports, 2021
Summary: Prdm12 is a key transcription factor in nociceptor neurogenesis. Mutations of Prdm12 cause congenital insensitivity to pain (CIP) from failure of nociceptor development.
Mark A. Landy, Megan Goyal, Katherine M. Casey, Chen Liu, Helen C. Lai   +4 more
doaj   +1 more source