Results 21 to 30 of about 86,700,063 (188)

Congenital insensitivity to pain: Case report of a rare entity

Indian Journal of Paediatric Dermatology, 2018
Hereditary sensory and autonomic neuropathies (HSANs) are a group of disorders characterized by insensitivity to noxious stimuli and autonomic dysfunction, associated with pathological abnormalities of the peripheral nerves.
Swati Dahiya, Kondajji Ramchandra Vijayalakshmi, Mubeen Khan   +2 more
doaj   +2 more sources

Congenital insensitivity to pain and anhidrosis: A case report from South India

Indian Journal of Dermatology, 2012
Congenital insensitivity to pain with anhidrosis, also known as hereditary sensory and autonomic neuropathy type IV, is an autosomal recessive disorder characterized by the congenital lack of pain sensation, inability to sweat, episodes of recurrent ...
Carounanidy Udayashankar, P Oudeacoumar, Amiya Kumar Nath   +2 more
doaj   +2 more sources

Congenital insensitivity to pain and anhydrosis syndrome

Indian Dermatology Online Journal, 2018
Isa An, Derya Ucmak
doaj   +3 more sources

Congenital Insensitivity to Pain with Anhidrosis in an Iranian Patient

Basic and Clinical Neuroscience, 2013
Congenital insensitivity to pain with anhidrosis is a rare disease of the nervous system which causes one to lose his/her feeling of pain. The disease is subtype four of hereditary sensory and autonomic neuropathy (HSAN IV) that results from NTRK1 gene ...
Nasrollah Saleh-gohari, Marzye Mohammadi-Anaie   +1 more
doaj   +3 more sources

CONGENITAL INSENSITIVITY TO PAIN WITH ANHYDROSIS

Gomal Journal of Medical Sciences, 2016
Congenital insensitivity to pain with anhydrosis (CIPA) is a rare genetic disorder characterized by inability to feel pain and temperature, and decreased or absent sweating.
Muhammad shafiq Khan, Aftab Hussain, Muhammad Javed Khan   +2 more
doaj   +1 more source

A Systematic Review of Congenital Insensitivity to Pain, a Rare Disease [PDF]

Journal of Personalized Medicine
Andres Reinoso Cobo, Jonathan Cortes-Martín, Juan Carlos Sánchez Garcia   +2 more
exaly   +2 more sources

Case report of a 7-year-old CIPA child with multiple debridement's and amputations.

International Journal of Endorsing Health Science Research, 2021
Background: Congenital Insensitivity to Pain (CIPA), otherwise known as Hereditary Sensory and Autonomic Neuropathy Type IV (HSAN IV), is a rarely occurring autosomal recessive disorder encompassed by a group of hereditary and sensory autonomic ...
Syed Ali Haider Zaidi, Sufyan Razak, Syeda Kiran Fatima, Hafiz Abdul Wase, Syed Mohammad Haider Zaidi, Zeeshan Yousuf, Farah Naz, Bilal Yousuf   +7 more
doaj   +1 more source

Congenital Insensitivity to Pain with Anhidrosis (CIPA) Syndrome; A Rare Genetic Disorder Case Story

Case Reports in Clinical Practice, 2022
Congenital insensitivity to pain with anhidrosis (CIPA) is the subtype four of hereditary sensory and autonomic neuropathy (HASN IV), caused by a defect in the NTRK1 gene and presenting early in life.
Zahra Nafei, Marjan Jafari
doaj   +1 more source

Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation

Cell Reports, 2021
Summary: Prdm12 is a key transcription factor in nociceptor neurogenesis. Mutations of Prdm12 cause congenital insensitivity to pain (CIP) from failure of nociceptor development.
Mark A. Landy, Megan Goyal, Katherine M. Casey, Chen Liu, Helen C. Lai   +4 more
doaj   +1 more source

Novel missense mutations contribute to congenital insensitivity to pain: Unexpected correlation between electrophysiological characterization and clinical phenotype

Molecular Pain, 2020
Congenital insensitivity to pain (OMIM 243000) is an extremely rare disorder caused by loss-of-function mutations in SCN9A encoding Nav1.7. Although the SCN9A mutations and phenotypes of painlessness and anosmia/hyposmia in patients are previously well ...
Jiaoli Sun, Lulu Li, Luyao Yang, Guangyou Duan, Tingbin Ma, Ningbo Li, Yi Liu, Jing Yao, Jing Yu Liu, Xianwei Zhang   +9 more
doaj   +1 more source